diff --git a/scripts/modules/elastic_stack.py b/scripts/modules/elastic_stack.py
index 37d08760e..d11291ffa 100644
--- a/scripts/modules/elastic_stack.py
+++ b/scripts/modules/elastic_stack.py
@@ -67,6 +67,7 @@ def __init__(self, **options):
         elif self.at_least_version("7.3"):
             self.apm_server_command_args.extend([
                 ("apm-server.kibana.enabled", "true"),
+                ("apm-server.agent.config.cache.expiration", "1s"),
                 ("apm-server.kibana.host", self.DEFAULT_KIBANA_HOST)])
 
         if self.options.get("enable_kibana", True):
diff --git a/scripts/tests/localsetup_tests.py b/scripts/tests/localsetup_tests.py
index de674bdcc..bf7fa528d 100644
--- a/scripts/tests/localsetup_tests.py
+++ b/scripts/tests/localsetup_tests.py
@@ -818,7 +818,7 @@ def test_start_master_default(self):
                     -E, 'setup.kibana.host=kibana:5601', -E, setup.template.settings.index.number_of_replicas=0,
                     -E, setup.template.settings.index.number_of_shards=1, -E, setup.template.settings.index.refresh_interval=1ms,
                     -E, monitoring.elasticsearch=true, -E, monitoring.enabled=true,
-                    -E, apm-server.kibana.enabled=true, -E, 'apm-server.kibana.host=kibana:5601',
+                    -E, apm-server.kibana.enabled=true, -E, apm-server.agent.config.cache.expiration=1s, -E, 'apm-server.kibana.host=kibana:5601',
                     -E, 'output.elasticsearch.hosts=["elasticsearch:9200"]', -E, output.elasticsearch.enabled=true,
                     -E, "output.elasticsearch.pipelines=[{pipeline: 'apm'}]", -E, 'apm-server.register.ingest.pipeline.enabled=true'
                     ]
diff --git a/scripts/tests/service_tests.py b/scripts/tests/service_tests.py
index 4bdbbf370..619442116 100644
--- a/scripts/tests/service_tests.py
+++ b/scripts/tests/service_tests.py
@@ -662,7 +662,7 @@ def test_dashboards(self):
     def test_apm_server_acm(self):
         apm_server = ApmServer(version="7.3").render()["apm-server"]
         self.assertTrue("apm-server.kibana.enabled=true" in apm_server["command"],
-                        "APM Server Kbana enabled by default")
+                        "APM Server Kibana enabled by default")
         self.assertTrue("apm-server.kibana.host=kibana:5601" in apm_server["command"],
                         "APM Server Kibana host set by default")
 
diff --git a/tests/agent/__init__.py b/tests/agent/__init__.py
index e69de29bb..b09b9b1c2 100644
--- a/tests/agent/__init__.py
+++ b/tests/agent/__init__.py
@@ -0,0 +1,48 @@
+from contextlib import contextmanager
+import requests
+import time
+from urllib.parse import urljoin
+
+from tests.fixtures import default
+
+
+@contextmanager
+def remote_config(kibana_url, sampling_rate=1.0):
+    def data(sample_rate):
+        return {
+            "agent_name": "python",
+            "service": {"name": default.from_env('FLASK_SERVICE_NAME')},
+            "settings": {"transaction_sample_rate": sample_rate}
+        }
+
+    headers = {"Content-Type": "application/json", "kbn-xsrf": "1"}
+    wait = 1.5  # just higher than apm-server.agent.config.cache.expiration
+
+    try:
+        r = requests.post(
+            urljoin(kibana_url, "/api/apm/settings/agent-configuration/new"),
+            headers=headers,
+            json=data(sampling_rate),
+        )
+        r.raise_for_status()
+        config_id = r.json()["_id"]
+        time.sleep(wait)  # give enough time to agent to pick up the config
+
+        yield config_id
+
+    finally:
+        # revert to original
+        r2 = requests.put(
+            urljoin(kibana_url, "/api/apm/settings/agent-configuration/" + config_id),
+            headers=headers,
+            json=data(1.0),
+        )
+        r2.raise_for_status()
+        time.sleep(wait)
+
+        r3 = requests.delete(
+            urljoin(kibana_url, "/api/apm/settings/agent-configuration/" + config_id),
+            headers=headers,
+        )
+        r3.raise_for_status()
+        time.sleep(wait)
diff --git a/tests/agent/test_python.py b/tests/agent/test_python.py
index 4eabcbb93..f465b2007 100644
--- a/tests/agent/test_python.py
+++ b/tests/agent/test_python.py
@@ -1,6 +1,6 @@
 import pytest
 
-from tests import utils
+from tests import utils, agent
 from tests.agent.concurrent_requests import Concurrent
 
 
@@ -27,6 +27,15 @@ def test_concurrent_req_flask(flask):
     Concurrent(flask.apm_server.elasticsearch, [foo], iters=2).run()
 
 
+@pytest.mark.version
+@pytest.mark.flask
+def test_req_flask_agent_config(flask, kibana):
+    with agent.remote_config(kibana.url, sampling_rate=0.0):
+        # 1 transaction, 0 spans
+        utils.check_agent_transaction(
+            flask.foo, flask.apm_server.elasticsearch, ct=1)
+
+
 @pytest.mark.version
 @pytest.mark.flask
 def test_concurrent_req_flask_foobar(flask):