diff --git a/DEPS b/DEPS
index f90786e36c150..4ba5a897c3461 100644
--- a/DEPS
+++ b/DEPS
@@ -2,7 +2,7 @@ gclient_gn_args_from = 'src'
 
 vars = {
   'chromium_version':
-    '110.0.5481.38',
+    '110.0.5481.52',
   'node_version':
     'v18.12.1',
   'nan_version':
diff --git a/patches/chromium/can_create_window.patch b/patches/chromium/can_create_window.patch
index 431ebd46f5515..e91d0c5022652 100644
--- a/patches/chromium/can_create_window.patch
+++ b/patches/chromium/can_create_window.patch
@@ -210,10 +210,10 @@ index a50a83d36f9172add44867ee0b0f1c89779b387e..c4ac7d4c885e764cfcfc3f2cd25e31b4
  
  }  // namespace blink
 diff --git a/third_party/blink/renderer/core/frame/local_dom_window.cc b/third_party/blink/renderer/core/frame/local_dom_window.cc
-index 6f6b091a3c0e1b0bc65a72bbb4adb65439bd58c1..89651dea92b168c30a1212938b689d4b47953be1 100644
+index b072b4ae6c85ce5a1f3b4249ebf556e331624771..e387c4dfbae62f60072a1700e105960da719ef86 100644
 --- a/third_party/blink/renderer/core/frame/local_dom_window.cc
 +++ b/third_party/blink/renderer/core/frame/local_dom_window.cc
-@@ -2207,6 +2207,8 @@ DOMWindow* LocalDOMWindow::open(v8::Isolate* isolate,
+@@ -2210,6 +2210,8 @@ DOMWindow* LocalDOMWindow::open(v8::Isolate* isolate,
    WebWindowFeatures window_features =
        GetWindowFeaturesFromString(features, entered_window, completed_url);
  
diff --git a/patches/chromium/preconnect_manager.patch b/patches/chromium/preconnect_manager.patch
index 2e6aae4a53a27..12ac5fd538484 100644
--- a/patches/chromium/preconnect_manager.patch
+++ b/patches/chromium/preconnect_manager.patch
@@ -10,7 +10,7 @@ in favor of defining PreconnectRequest in this file since we don't build
 the header.
 
 diff --git a/chrome/browser/predictors/preconnect_manager.cc b/chrome/browser/predictors/preconnect_manager.cc
-index de39505b1e515559182b6b3f25ffbe96f0b8262b..a040d30dd35f3f6c4dda58fb9d2e3e537ecbb9f7 100644
+index d3f1b0daafb8a3a12f6f5a26cb24c98312b38f8d..00dc7871d41efe918c709a0e2728832c10162893 100644
 --- a/chrome/browser/predictors/preconnect_manager.cc
 +++ b/chrome/browser/predictors/preconnect_manager.cc
 @@ -10,9 +10,11 @@
@@ -63,7 +63,7 @@ index de39505b1e515559182b6b3f25ffbe96f0b8262b..a040d30dd35f3f6c4dda58fb9d2e3e53
  
  void PreconnectManager::Start(const GURL& url,
 diff --git a/chrome/browser/predictors/preconnect_manager.h b/chrome/browser/predictors/preconnect_manager.h
-index 5f7e0db497a48829a330d7aae63d0da34cca7e33..d25f97a11174cb6e28b961cd7fc59ba3831e7a54 100644
+index d18470c05cdaffbc48b83cc0c76f7085442dccce..0c0a3f11a2da083ef5437a0e6abcf91afbcf9df3 100644
 --- a/chrome/browser/predictors/preconnect_manager.h
 +++ b/chrome/browser/predictors/preconnect_manager.h
 @@ -17,7 +17,9 @@