diff --git a/test/test_browser.py b/test/test_browser.py
index e4e1191770d4c..9ece9a00a2d76 100644
--- a/test/test_browser.py
+++ b/test/test_browser.py
@@ -2545,7 +2545,7 @@ def test_html5_core(self, opts):
     self.btest_exit('test_html5_core.c', cflags=opts)
 
   def test_html5_remove_event_listener(self):
-    self.btest_exit('test_html5_remove_event_listener.c')
+    self.btest_exit('test_html5_remove_event_listener.c', cflags=[f'-DSAFARI_SUPPORT={int(not self.is_wasm64())}'])
 
   @parameterized({
     '': ([],),
diff --git a/test/test_html5_remove_event_listener.c b/test/test_html5_remove_event_listener.c
index 394e7afe31ee7..0fde8527e762e 100644
--- a/test/test_html5_remove_event_listener.c
+++ b/test/test_html5_remove_event_listener.c
@@ -45,6 +45,11 @@ bool mouse_callback_1(int eventType, const EmscriptenMouseEvent *e, void *userDa
   return 0;
 }
 
+bool screen_callback(int eventType, const EmscriptenFullscreenChangeEvent *fullscreenChangeEvent, void *userData) {
+  printf("screen_callback: eventType=%d, userData=%s\n", eventType, (char const *) userData);
+  return 0;
+}
+
 void checkCount(int count) {
   int eventHandlersCount = EM_ASM_INT({ return JSEvents.eventHandlers.length; });
   printf("Detected [%d] handlers\n", eventHandlersCount);
@@ -130,5 +135,22 @@ int main() {
 
   checkCount(2);
 
+  // internally, emscripten_set_fullscreenchange_callback can set 2 event handlers ("webkitfullscreenchange" and "fullscreenchange")
+  ret = emscripten_set_fullscreenchange_callback(EMSCRIPTEN_EVENT_TARGET_WINDOW, NULL, useCapture, screen_callback);
+  ASSERT_RESULT(emscripten_set_fullscreenchange_callback);
+
+#if SAFARI_SUPPORT == 1
+  // 2 events handlers are set when there is safari support
+  checkCount(4);
+#else
+  checkCount(3);
+#endif
+
+  // we make sure that the 2 event handlers get removed (#25846)
+  ret = emscripten_html5_remove_event_listener(EMSCRIPTEN_EVENT_TARGET_WINDOW, NULL, EMSCRIPTEN_EVENT_FULLSCREENCHANGE, screen_callback);
+  ASSERT_RESULT(emscripten_html5_remove_event_listener);
+
+  checkCount(2);
+
   return 0;
 }