diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
new file mode 100644
index 0000000..2b997fe
--- /dev/null
+++ b/.github/workflows/main.yml
@@ -0,0 +1,32 @@
+on:
+  push:
+    branches:
+    - master
+    - ci-test
+  pull_request:
+    branches:
+    - master
+
+name: Run Tox tests
+
+jobs:
+  tox_test:
+    name: Tox test
+    steps:
+    - uses: actions/checkout@v2
+    - name: Run Tox tests
+      id: test
+      uses: fedora-python/tox-github-action@master
+      with:
+        tox_env: ${{ matrix.tox_env }}
+        dnf_install: /usr/bin/make
+    strategy:
+      matrix:
+        tox_env: [
+            py27-c90, py35-c90, py36-c90,
+            py27-c99, py35-c99, py36-c99, py37-c99, py38-c99, py39-c99, py310-c99,
+            py27-c90, py35-cpp, py36-cpp, py37-cpp, py38-cpp, py39-cpp, py310-cpp,
+        ]
+
+    # Use GitHub's Linux Docker host
+    runs-on: ubuntu-latest
diff --git a/.travis.yml b/.travis.yml
deleted file mode 100644
index 63c3b23..0000000
--- a/.travis.yml
+++ /dev/null
@@ -1,33 +0,0 @@
-language: python
-arch:
-  - amd64
-  - ppc64le
-python:
-  - "2.7"
-  - "3.4"
-  - "3.5"
-  - "3.5"
-  - "3.6"
-  - "3.7"
-  - "3.8"
-  - "3.9"
-  - "nightly"
-
-env:
-    - TEST_USE_CPP=no CFLAGS="-Werror -Wall -std=c90 -Wno-error=strict-aliasing"
-    - TEST_USE_CPP=no CFLAGS="-Werror -Wall -std=c99 -Wno-error=strict-aliasing"
-    - TEST_USE_CPP=yes CFLAGS="-Werror -Wall -Wno-error=strict-aliasing"
-
-matrix:
-  exclude:
-  # CPython 3.8+ won't compile with c90.
-  - python: "3.8"
-    env: TEST_USE_CPP=no CFLAGS="-Werror -Wall -std=c90 -Wno-error=strict-aliasing"
-  - python: "3.9"
-    env: TEST_USE_CPP=no CFLAGS="-Werror -Wall -std=c90 -Wno-error=strict-aliasing"
-  - python: "nightly"
-    env: TEST_USE_CPP=no CFLAGS="-Werror -Wall -std=c90 -Wno-error=strict-aliasing"
-
-script: make test-python
-
-sudo: false