If a tooltip contains a link, The only way to make it clickable is to set hideDelay to a high value. Otherwise, the tip disappears before the cursor reaches the link. If the user doesn't want to click, it is annoying to wait for the tooltip to disappear.
In my case 1 second is not enough for the link but too much for the tooltip itself.
Please have a look at demo 16 (Element as tooltip) at http://www.nickstakenburg.com/projects/prototip/ which shows what I like to see.
How about implementing this feature in OpenTip?