diff --git a/src/rpc/node.cpp b/src/rpc/node.cpp
index 45053f882dd83a..02e56e61eb8a37 100644
--- a/src/rpc/node.cpp
+++ b/src/rpc/node.cpp
@@ -26,6 +26,7 @@
 #include <univalue.h>
 #include <util/any.h>
 #include <util/check.h>
+#include <util/time.h>
 
 #include <stdint.h>
 #ifdef HAVE_MALLOC_INFO
@@ -58,9 +59,11 @@ static RPCHelpMan setmocktime()
     LOCK(cs_main);
 
     const int64_t time{request.params[0].getInt<int64_t>()};
-    if (time < 0) {
-        throw JSONRPCError(RPC_INVALID_PARAMETER, strprintf("Mocktime cannot be negative: %s.", time));
+    constexpr int64_t max_time{Ticks<std::chrono::seconds>(std::chrono::nanoseconds::max())};
+    if (time < 0 || time > max_time) {
+        throw JSONRPCError(RPC_INVALID_PARAMETER, strprintf("Mocktime must be in the range [0, %s], not %s.", max_time, time));
     }
+
     SetMockTime(time);
     const NodeContext& node_context{EnsureAnyNodeContext(request.context)};
     for (const auto& chain_client : node_context.chain_clients) {
diff --git a/test/functional/rpc_uptime.py b/test/functional/rpc_uptime.py
index cb99e483ece293..f8df59d02ad39d 100755
--- a/test/functional/rpc_uptime.py
+++ b/test/functional/rpc_uptime.py
@@ -23,7 +23,7 @@ def run_test(self):
         self._test_uptime()
 
     def _test_negative_time(self):
-        assert_raises_rpc_error(-8, "Mocktime cannot be negative: -1.", self.nodes[0].setmocktime, -1)
+        assert_raises_rpc_error(-8, "Mocktime must be in the range [0, 9223372036], not -1.", self.nodes[0].setmocktime, -1)
 
     def _test_uptime(self):
         wait_time = 10