diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index 8db6d83..1e1bd60 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -20,7 +20,7 @@ jobs:
         tox_env: ${{ matrix.tox_env }}
     strategy:
       matrix:
-        tox_env: [py36, py39, py310, py311, py312, py313, py314, pypy2, pypy3]
+        tox_env: [py36, py39, py310, py311, py312, py313, py314, pypy3]
 
     # Use GitHub's Linux Docker host
     runs-on: ubuntu-latest
diff --git a/README.md b/README.md
index f5d3f7b..b4ec89f 100644
--- a/README.md
+++ b/README.md
@@ -62,6 +62,11 @@ Until version 0.4, this action always used the latest [fedora-python-tox](https:
 image. Since version 34.0, the first number in the version (also sometimes
 referred to as the "major version") represents the release of Fedora used in the image.
 
+### v43.0
+
+* Uses Fedora 43 as the base container image.
+* Running pypy2 tox environment no longer works out of the box, see [tox documentation for details](https://tox.wiki/en/4.35.0/faq.html#testing-end-of-life-python-versions).
+
 ### v42.0
 
 * Uses Fedora 42 as the base container image.
diff --git a/action.yaml b/action.yaml
index 64953a0..89fedf0 100644
--- a/action.yaml
+++ b/action.yaml
@@ -16,7 +16,7 @@ inputs:
 
 runs:
   using: docker
-  image: docker://fedorapython/fedora-python-tox:f42
+  image: docker://fedorapython/fedora-python-tox:f43
   env:
     TOXENV: ${{ inputs.tox_env }}
     DNF_INSTALL: ${{ inputs.dnf_install }}
diff --git a/pyproject.toml b/pyproject.toml
index 82cb294..98e922f 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -5,7 +5,7 @@ build-backend = "setuptools.build_meta"
 [tool.tox]
 legacy_tox_ini = """
 [tox]
-envlist = py36,py39,py310,py311,py312,py313,py314,py314t,pypy2,pypy3
+envlist = py36,py39,py310,py311,py312,py313,py314,py314t,pypy3
 skipsdist = True
 
 [testenv]