Matched Interaction Across Tissues (MIxT) web application
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README.md

MIxT

Matched Interaction Across Tissues (MIxT) is a system designed for exploring and comparing transcriptional profiles from two or more matched tissues across individuals. Here, the MIxT system is applied to tumor and blood transcriptional profiles from breast cancer patients from the Norwegian Women and Cancer study.

Users can browse through all the results generated for this study, visualize gene co-expression networks and expression heatmaps, and search for genes, gene lists, and pathways.

The application runs at mixt-blood-tumor.bci.mcgill.ca.

Screenshot of the welcome page

System

MIxT consist of two main components: the web application and the compute backend. The compute backend provides data and analyses, and the web application allows users to view and explore the results. We use the r package in Kvik to run the compute backend.

Install and run

There are two options for installing and running the MIxT web application, either compile and run on your machine, or use the Docker Image.

Compile and run

  • First install go
  • $ go get github.com/fjukstad/mixt
  • $ cd $GOPATH/src/github.com/fjukstad/mixt
  • $ mixt
  • Open localhost:8004

Docker

  • Install Docker
  • $ docker run -p 8004:80 fjukstad/mixt
  • Open localhost:8004