diff --git a/cypress/e2e/consortia/switch-active-affiliation-option-is-not-displayed.cy.js b/cypress/e2e/consortia/switch-active-affiliation-option-is-not-displayed.cy.js
new file mode 100644
index 0000000000..9dc65c13f4
--- /dev/null
+++ b/cypress/e2e/consortia/switch-active-affiliation-option-is-not-displayed.cy.js
@@ -0,0 +1,52 @@
+import Permissions from '../../support/dictionary/permissions';
+import Affiliations, { tenantNames } from '../../support/dictionary/affiliations';
+import Users from '../../support/fragments/users/users';
+import TopMenu from '../../support/fragments/topMenu';
+import ConsortiumManager from '../../support/fragments/settings/consortium-manager/consortium-manager';
+
+describe('Consortia', () => {
+  let user;
+
+  before(() => {
+    cy.getAdminToken();
+  });
+
+  after('Delete users, data', () => {
+    cy.resetTenant();
+    cy.getAdminToken();
+    Users.deleteViaApi(user.userId);
+  });
+
+  it(
+    'C388499: "Switch active affiliation" option is NOT displayed when a user has only one assigned affiliation (consortia)(thunderjet)',
+    { tags: ['criticalPath', 'thunderjet'] },
+    () => {
+      cy.createTempUser([
+        Permissions.consortiaSettingsConsortiaAffiliationsEdit.gui,
+        Permissions.uiUsersPermissions.gui,
+        Permissions.uiUserEdit.gui,
+        Permissions.uiUsersPermissionsView.gui,
+        Permissions.uiUsersView.gui,
+      ])
+        .then((userProperties) => {
+          user = userProperties;
+          cy.login(user.username, user.password, {
+            path: TopMenu.usersPath,
+            waiter: Users.waitLoading,
+          });
+          cy.wait(8000);
+          ConsortiumManager.checkCurrentTenantInTopMenu(tenantNames.central);
+          ConsortiumManager.switchActiveAffiliationIsAbsent();
+        })
+        .then(() => {
+          cy.getAdminToken();
+          cy.assignAffiliationToUser(Affiliations.College, user.userId);
+          cy.setTenant(Affiliations.College);
+        });
+      cy.reload();
+      ConsortiumManager.switchActiveAffiliationExists();
+      ConsortiumManager.switchActiveAffiliation(tenantNames.college);
+      ConsortiumManager.checkCurrentTenantInTopMenu(tenantNames.college);
+    },
+  );
+});
diff --git a/cypress/support/fragments/settings/consortium-manager/consortium-manager.js b/cypress/support/fragments/settings/consortium-manager/consortium-manager.js
index a33e368969..6c5ac916f3 100644
--- a/cypress/support/fragments/settings/consortium-manager/consortium-manager.js
+++ b/cypress/support/fragments/settings/consortium-manager/consortium-manager.js
@@ -9,6 +9,9 @@ import {
   HTML,
 } from '../../../../../interactors';
 
+const myProfileButton = Button({ ariaLabel: 'My profile' });
+const switchActiveAffiliationButton = Button('Switch active affiliation');
+
 export default {
   waitLoading() {
     cy.expect(Section({ id: 'app-settings-nav-pane' }).exists());
@@ -60,8 +63,8 @@ export default {
   switchActiveAffiliation(tenantName) {
     cy.wait(8000);
     cy.do([
-      Button({ ariaLabel: 'My profile' }).click(),
-      Button('Switch active affiliation').click(),
+      myProfileButton.click(),
+      switchActiveAffiliationButton.click(),
       Modal('Select affiliation')
         .find(Button({ id: 'consortium-affiliations-select' }))
         .click(),
@@ -71,11 +74,21 @@ export default {
     cy.wait(8000);
   },
 
+  switchActiveAffiliationIsAbsent() {
+    cy.wait(8000);
+    cy.do(myProfileButton.click());
+    cy.expect(switchActiveAffiliationButton.absent());
+    cy.do(myProfileButton.click());
+  },
+
+  switchActiveAffiliationExists() {
+    cy.wait(8000);
+    cy.do(myProfileButton.click());
+    cy.expect(switchActiveAffiliationButton.exists());
+    cy.do(myProfileButton.click());
+  },
+
   checkCurrentTenantInTopMenu(tenantName) {
-    cy.expect(
-      Button({ ariaLabel: 'My profile' })
-        .find(HTML({ text: including(tenantName) }))
-        .exists(),
-    );
+    cy.expect(myProfileButton.find(HTML({ text: including(tenantName) })).exists());
   },
 };