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flexible tool to search allen brain atlases
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fredpdavis/allenminer
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ALLENMINER: a tool to find patterns of interest in the Allen Brain Atlas ======================================================================== Version 2.1; Dec 10, 2015. http://fredpdavis.com/allenminer Copyright 2008, 2012, 2015 Fred P. Davis What is ALLENMINER? ------------------- ALLENMINER searches for genes that express in patterns of interest in the developing or adult mouse Allen Brain Atlases (ABA). It can search in any region of interest for genes that: 1. express 2. express specifically 3. express non-uniformly 4. express in a graded fashion 5. express in a pattern similar to a query gene The region of interest can be specified as a set of brain region names or as x,y,z bounds of a cuboid region of interest. The code includes several routines that are generally useful for processing ABA data files, including parsers for XML and XPZ files. Besides accessing the raw data, these routines are useful for visualizing ABA expression files on platforms where the ABA BrainExplorer application is not available (eg, GNU/Linux). For example, all ABA expression files can be converted to PDB (protein data bank) format for visualization in protein structure viewers, such as PyMOL (http://pymol.org). I began to develop ALLENMINER at the HHMI Janelia Research Campus and continue to maintain it at NIH/NIAMS. What's new? ------------ Version 2.1 is compatible with the latest adult (v7) and developing (v6) brain atlases. Documentation ------------- docs/allenminer_user_manual.pdf offers detailed instruction on installation and usage. This README offers a quick guide to a small subset of the features. Citing ALLENMINER ----------------- A tool for identification of genes expressed in patterns of interest using the Allen Brain Atlas. Fred P. Davis and Sean R. Eddy. Bioinformatics 2009. 25(13): 1647-54. doi:10.1093/bioinformatics/btp288 Contact information ------------------- Fred P. Davis http://fredpdavis.com fredpdavis@gmail.com This file is part of ALLENMINER. ALLENMINER is free software: you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation, either version 3 of the License, or (at your option) any later version. ALLENMINER is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. You should have received a copy of the GNU General Public License along with ALLENMINER. If not, see <http://www.gnu.org/licenses/>. ----------------------------------------------------------------------------
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