diff --git a/biology/ngs-sdk/Makefile b/biology/ngs-sdk/Makefile
index a42c04fe0afa9..4bba0411e5f7a 100644
--- a/biology/ngs-sdk/Makefile
+++ b/biology/ngs-sdk/Makefile
@@ -14,8 +14,8 @@ BROKEN_aarch64=		fails to configure: unsupported architecture 'FreeBSD'
 BROKEN_armv6=		fails to configure: unsupported architecture 'FreeBSD':'arm'
 BROKEN_armv7=		fails to configure: unsupported architecture 'FreeBSD':'arm'
 BROKEN_riscv64=		fails to configure: unsupported architecture 'FreeBSD'
-NOT_FOR_ARCHS=		powerpc64
-NOT_FOR_ARCHS_REASON=	os-arch.prl needs to be taught about powerpc64
+NOT_FOR_ARCHS=		powerpc powerpc64 powerpc64le
+NOT_FOR_ARCHS_REASON=	os-arch.prl needs to be taught about powerpc64, etc
 
 USES=		compiler:c++11-lang gmake perl5
 USE_PERL5=	build