diff --git a/science/afni/Makefile b/science/afni/Makefile
index cbdd32d54c161..38412036cef66 100644
--- a/science/afni/Makefile
+++ b/science/afni/Makefile
@@ -1,6 +1,6 @@
 PORTNAME=		afni
 DISTVERSIONPREFIX=	AFNI_
-DISTVERSION=		21.1.09
+DISTVERSION=		21.1.12
 CATEGORIES=		science biology graphics perl5 python
 
 MAINTAINER=	fernape@FreeBSD.org
diff --git a/science/afni/distinfo b/science/afni/distinfo
index a9c993cf7ea9f..f186b133d3907 100644
--- a/science/afni/distinfo
+++ b/science/afni/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1622390715
-SHA256 (afni-afni-AFNI_21.1.09_GH0.tar.gz) = 50c038f18d7c49db0d046c2a12b98907a36662e558d8628f299800051b341057
-SIZE (afni-afni-AFNI_21.1.09_GH0.tar.gz) = 43377177
+TIMESTAMP = 1623748135
+SHA256 (afni-afni-AFNI_21.1.12_GH0.tar.gz) = b390c6acf44c36fb5a9f7a58d71dd34d8abd429640fe4238c99967521e6d8492
+SIZE (afni-afni-AFNI_21.1.12_GH0.tar.gz) = 43443451
diff --git a/science/afni/files/patch-crorden_dcm2niix__console_makefile b/science/afni/files/patch-crorden_dcm2niix__console_makefile
index c20e41c355ea4..7816c4ff42c57 100644
--- a/science/afni/files/patch-crorden_dcm2niix__console_makefile
+++ b/science/afni/files/patch-crorden_dcm2niix__console_makefile
@@ -1,4 +1,4 @@
---- crorden/dcm2niix_console/makefile.orig	2019-05-12 14:54:20 UTC
+--- crorden/dcm2niix_console/makefile.orig	2021-06-15 02:26:33 UTC
 +++ crorden/dcm2niix_console/makefile
 @@ -1,8 +1,8 @@
  # Regular use
@@ -9,14 +9,18 @@
 -#CFLAGS=-g
 +#CXXFLAGS=-g
  
- #run "make" for default build
- #run "JPEGLS=1 make" for JPEGLS build
-@@ -14,8 +14,8 @@ endif
- ifneq ($(OS),Windows_NT)
- 	OS = $(shell uname)
-  	ifeq "$(OS)" "Darwin"
--		CFLAGS=-dead_strip -O3
-+		CXXFLAGS=-dead_strip -O3
+ #Leak tests:
+ # https://clang.llvm.org/docs/AddressSanitizer.html
+@@ -23,7 +23,7 @@ ifneq ($(OS),Windows_NT)
+ 		#CFLAGS= -O3
+ 		# CFLAGS=-O3 -sectcreate __TEXT __info_plist Info.plist
+ 		# rickr - ponder -sectcreate later
+-		CFLAGS=-O3
++		CXXFLAGS=-O3
+ 		#Apple notarization requires a Info.plist
+ 		# For .app bundles, the Info.plist is a separate file, for executables it is appended as a section
+ 		#you can check that the Info.plist section has been inserted with either of these commands
+@@ -33,4 +33,4 @@ ifneq ($(OS),Windows_NT)
  	endif
  endif
  all:
diff --git a/science/afni/pkg-plist b/science/afni/pkg-plist
index d3500404f35e3..c6ebae5a08b1c 100644
--- a/science/afni/pkg-plist
+++ b/science/afni/pkg-plist
@@ -36,6 +36,7 @@ bin/2dcat
 bin/2perm
 bin/2swap
 bin/3dABoverlap
+bin/3dmaxdisp
 bin/3dAFNIto3D
 bin/3dAFNItoANALYZE
 bin/3dAFNItoNIFTI
@@ -463,6 +464,7 @@ bin/SurfDsetInfo
 bin/SurfExtrema
 bin/SurfFWHM
 bin/SurfInfo
+bin/SurfLocalstat
 bin/SurfMeasures
 bin/SurfPatch
 bin/SurfQual