diff --git a/fury/ui/elements.py b/fury/ui/elements.py
index 9f3569d5e..57165c807 100644
--- a/fury/ui/elements.py
+++ b/fury/ui/elements.py
@@ -2068,6 +2068,7 @@ def __init__(self, items=[], position=(0, 0), size=(300, 200),
         self.scroll_active_color = scroll_bar_active_color
         self.scroll_inactive_color = scroll_bar_inactive_color
         self.menu_opacity = menu_opacity
+        self.callback_flag = False
 
         # Define subcomponent sizes.
         self.text_block_size = (int(0.8*size[0]), int(0.3*size[1]))
@@ -2246,20 +2247,26 @@ def select_option_callback(self, i_ren, _obj, listboxitem):
         """
 
         # Set the Text of TextBlock2D to the text of listboxitem
-        self._selection = listboxitem.element
-        self._selection_ID = self.items.index(self._selection)
+        # The callback_flag prevents unnecessary loops
+        if not self.callback_flag:
+            self._selection = listboxitem.element
+            self._selection_ID = self.items.index(self._selection)
 
-        self.selection_box.message = self._selection
-        clip_overflow(self.selection_box,
-                      self.selection_box.background.size[0])
-        self.drop_down_menu.set_visibility(False)
-        self._menu_visibility = False
+            self.selection_box.message = self._selection
+            clip_overflow(self.selection_box,
+                          self.selection_box.background.size[0])
 
-        self.drop_down_button.next_icon()
+            self.drop_down_menu.set_visibility(False)
+            self._menu_visibility = False
 
-        self.on_change(self)
+            self.drop_down_button.next_icon()
+
+            self.on_change(self)
+
+            i_ren.force_render()
+            self.callback_flag = True
+            self.drop_down_menu.callback_flag = True
 
-        i_ren.force_render()
         i_ren.event.abort()
 
     def menu_toggle_callback(self, i_ren, _vtkactor, _combobox):
@@ -2273,6 +2280,9 @@ def menu_toggle_callback(self, i_ren, _vtkactor, _combobox):
         combobox : :class:`ComboBox2D`
 
         """
+        self.callback_flag = False
+        self.drop_down_menu.callback_flag = False
+
         self._menu_visibility = not self._menu_visibility
         self.drop_down_menu.set_visibility(self._menu_visibility)
 
@@ -2373,6 +2383,7 @@ def __init__(self, values, position=(0, 0), size=(100, 300),
 
         self.position = position
         self.scroll_init_position = 0
+        self.callback_flag = False
         self.update()
 
         # Offer some standard hooks to the user.
@@ -2668,29 +2679,30 @@ def select(self, item, multiselect=False, range_select=False):
             multi_select is True.
 
         """
-        selection_idx = self.values.index(item.element)
-        if self.multiselection and range_select:
-            self.clear_selection()
-            step = 1 if selection_idx >= self.last_selection_idx else -1
-            for i in range(self.last_selection_idx,
-                           selection_idx + step,
-                           step):
-                self.selected.append(self.values[i])
+        if not self.callback_flag:
+            selection_idx = self.values.index(item.element)
+            if self.multiselection and range_select:
+                self.clear_selection()
+                step = 1 if selection_idx >= self.last_selection_idx else -1
+                for i in range(self.last_selection_idx,
+                               selection_idx + step,
+                               step):
+                    self.selected.append(self.values[i])
+
+            elif self.multiselection and multiselect:
+                if item.element in self.selected:
+                    self.selected.remove(item.element)
+                else:
+                    self.selected.append(item.element)
+                self.last_selection_idx = selection_idx
 
-        elif self.multiselection and multiselect:
-            if item.element in self.selected:
-                self.selected.remove(item.element)
             else:
+                self.clear_selection()
                 self.selected.append(item.element)
-            self.last_selection_idx = selection_idx
-
-        else:
-            self.clear_selection()
-            self.selected.append(item.element)
-            self.last_selection_idx = selection_idx
+                self.last_selection_idx = selection_idx
 
-        self.on_change()  # Call hook.
-        self.update()
+            self.on_change()  # Call hook.
+            self.update()
 
 
 class ListBoxItem2D(UI):