Matchmaker Exchange API
The Matchmaker Exchange (MME) API provides a shared language that databases can use to query each other to find similar patients. The API is build around a standardized patient profile that includes both phenotype and genotype information. Implementing the API involves parsing a query profile, identifying cases in your database that are similar, and returning a list of profiles for those cases.
Implementing the MME API
Version 1.0 (latest release):
Development version (master branch):
- API specification: search-api.md
Have a question? Send us an email at email@example.com or create a GitHub issue.
How to connect to another endpoint
- To query most MME services, you need to request an authentication token from that service. You can find a more detailed description here: join-protocol.md.
- To help securely share authentication tokens, the KEYS file contains GPG keys for at least one member of each MME team.
The wiki contains an up-to-date list of active endpoints: https://github.com/ga4gh/mme-apis/wiki/Endpoints
Open-source API implementations
The wiki contains a list of open-source implementations of the MME API: https://github.com/ga4gh/mme-apis/wiki/Implementations