diff --git a/sentry_sdk/integrations/openai.py b/sentry_sdk/integrations/openai.py
index e9bd2efa23..19d7717b3c 100644
--- a/sentry_sdk/integrations/openai.py
+++ b/sentry_sdk/integrations/openai.py
@@ -1,4 +1,5 @@
 from functools import wraps
+from collections.abc import Iterable
 
 import sentry_sdk
 from sentry_sdk import consts
@@ -17,14 +18,19 @@
 from typing import TYPE_CHECKING
 
 if TYPE_CHECKING:
-    from typing import Any, Iterable, List, Optional, Callable, AsyncIterator, Iterator
+    from typing import Any, List, Optional, Callable, AsyncIterator, Iterator
     from sentry_sdk.tracing import Span
 
 try:
     try:
-        from openai import NOT_GIVEN
+        from openai import NotGiven
     except ImportError:
-        NOT_GIVEN = None
+        NotGiven = None
+
+    try:
+        from openai import Omit
+    except ImportError:
+        Omit = None
 
     from openai.resources.chat.completions import Completions, AsyncCompletions
     from openai.resources import Embeddings, AsyncEmbeddings
@@ -204,12 +210,12 @@ def _set_input_data(span, kwargs, operation, integration):
     for key, attribute in kwargs_keys_to_attributes.items():
         value = kwargs.get(key)
 
-        if value is not NOT_GIVEN and value is not None:
+        if value is not None and _is_given(value):
             set_data_normalized(span, attribute, value)
 
     # Input attributes: Tools
     tools = kwargs.get("tools")
-    if tools is not NOT_GIVEN and tools is not None and len(tools) > 0:
+    if tools is not None and _is_given(tools) and len(tools) > 0:
         set_data_normalized(
             span, SPANDATA.GEN_AI_REQUEST_AVAILABLE_TOOLS, safe_serialize(tools)
         )
@@ -689,3 +695,15 @@ async def _sentry_patched_responses_async(*args, **kwargs):
         return await _execute_async(f, *args, **kwargs)
 
     return _sentry_patched_responses_async
+
+
+def _is_given(obj):
+    # type: (Any) -> bool
+    """
+    Check for givenness safely across different openai versions.
+    """
+    if NotGiven is not None and isinstance(obj, NotGiven):
+        return False
+    if Omit is not None and isinstance(obj, Omit):
+        return False
+    return True
diff --git a/tests/integrations/openai/test_openai.py b/tests/integrations/openai/test_openai.py
index 06e0a09fcf..276a1b4886 100644
--- a/tests/integrations/openai/test_openai.py
+++ b/tests/integrations/openai/test_openai.py
@@ -7,6 +7,11 @@
 except ImportError:
     NOT_GIVEN = None
 
+try:
+    from openai import omit
+except ImportError:
+    omit = None
+
 from openai import AsyncOpenAI, OpenAI, AsyncStream, Stream, OpenAIError
 from openai.types import CompletionUsage, CreateEmbeddingResponse, Embedding
 from openai.types.chat import ChatCompletion, ChatCompletionMessage, ChatCompletionChunk
@@ -1424,7 +1429,7 @@ async def test_streaming_responses_api_async(
 )
 @pytest.mark.parametrize(
     "tools",
-    [[], None, NOT_GIVEN],
+    [[], None, NOT_GIVEN, omit],
 )
 def test_empty_tools_in_chat_completion(sentry_init, capture_events, tools):
     sentry_init(