diff --git a/sentry_sdk/integrations/__init__.py b/sentry_sdk/integrations/__init__.py
index 4c286c87fe..b340dec36e 100644
--- a/sentry_sdk/integrations/__init__.py
+++ b/sentry_sdk/integrations/__init__.py
@@ -176,6 +176,8 @@ def iter_default_integrations(with_auto_enabling_integrations):
 
 _INTEGRATION_DEACTIVATES = {
     "langchain": {"openai", "anthropic"},
+    "openai_agents": {"openai"},
+    "pydantic_ai": {"openai", "anthropic"},
 }
 
 
diff --git a/tests/test_ai_integration_deactivation.py b/tests/test_ai_integration_deactivation.py
index 71ac4f70a9..dc8aef6be8 100644
--- a/tests/test_ai_integration_deactivation.py
+++ b/tests/test_ai_integration_deactivation.py
@@ -26,8 +26,29 @@
     has_anthropic = False
 
 
+try:
+    from sentry_sdk.integrations.openai_agents import OpenAIAgentsIntegration
+
+    has_openai_agents = True
+except Exception:
+    has_openai_agents = False
+
+try:
+    from sentry_sdk.integrations.pydantic_ai import PydanticAIIntegration
+
+    has_pydantic_ai = True
+except Exception:
+    has_pydantic_ai = False
+
+
 pytestmark = pytest.mark.skipif(
-    not (has_langchain and has_openai and has_anthropic),
+    not (
+        has_langchain
+        and has_openai
+        and has_anthropic
+        and has_openai_agents
+        and has_pydantic_ai
+    ),
     reason="Requires langchain, openai, and anthropic packages to be installed",
 )
 
@@ -36,6 +57,11 @@ def test_integration_deactivates_map_exists():
     assert "langchain" in _INTEGRATION_DEACTIVATES
     assert "openai" in _INTEGRATION_DEACTIVATES["langchain"]
     assert "anthropic" in _INTEGRATION_DEACTIVATES["langchain"]
+    assert "openai_agents" in _INTEGRATION_DEACTIVATES
+    assert "openai" in _INTEGRATION_DEACTIVATES["openai_agents"]
+    assert "pydantic_ai" in _INTEGRATION_DEACTIVATES
+    assert "openai" in _INTEGRATION_DEACTIVATES["pydantic_ai"]
+    assert "anthropic" in _INTEGRATION_DEACTIVATES["pydantic_ai"]
 
 
 def test_langchain_auto_deactivates_openai_and_anthropic(
@@ -104,13 +130,17 @@ def test_user_can_override_with_both_explicit_integrations(
     assert AnthropicIntegration in integration_types
 
 
-def test_disabling_langchain_allows_openai_and_anthropic(
+def test_disabling_integrations_allows_openai_and_anthropic(
     sentry_init, reset_integrations
 ):
     sentry_init(
         default_integrations=False,
         auto_enabling_integrations=True,
-        disabled_integrations=[LangchainIntegration],
+        disabled_integrations=[
+            LangchainIntegration,
+            OpenAIAgentsIntegration,
+            PydanticAIIntegration,
+        ],
     )
 
     client = get_client()