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Update README.md
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julianhess authored Aug 18, 2020
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Expand Up @@ -91,27 +91,6 @@ mutation in a single patient. Columns can be in any order, with names and
formats as follows. To provide maximal input flexibility, MutSig accepts
synonyms for each column name. Column names are case sensitive.

<!--* `chr`: Chromosome of the mutation. MutSig only analyzes mutations on autosomal or sex chromosomes, and does not consider the mitochondrial chromosome or unplaced/alternate contigs.
* Range: `(chr)?[1..24XY]`
* Synonyms: `Chromosome`
* `pos`: hg19 position of the mutation, 1-indexed.
* Regex: `[0-9]+`
* Synonyms: `Position`, `start`, `Start_position`
* `patient`: Unique identifier for the patient.
* Regex: `[A-Za-z0-9]+`
* Synonyms: `Tumor_Sample_Barcode`, `Patient_name`
* `ref_allele`: hg19 reference base(s) for the position. In the case of insertions, must be "-".
* Regex: `(-|[ACGT]+)`
* Synonyms: `Reference_Allele`
* `newbase`: Observed variant allele at the position. In the case of deletions, must be "-".
* Regex: `(-|[ACGT]+)`
* Synonyms: `Tumor_Allele`, `Tum_allele`, `Alt_allele`, `Alternate_allele`, `Tumor_Seq_Allele2` -->

Note that MutSig does not require any other mutation annotations; it infers everything else on its own.
* `chr`: Chromosome of the mutation. MutSig only analyzes mutations on
autosomal or sex chromosomes, and does not consider the
mitochondrial chromosome or unplaced/alternate contigs.
Expand All @@ -122,7 +101,7 @@ Note that MutSig does not require any other mutation annotations; it infers ever
* Regex: `[0-9]+`
* Synonyms: `Position`, `start`, `Start_position`

* gene: HUGO symbol for the gene containing this mutation, or "Unknown"
* `gene`: HUGO symbol for the gene containing this mutation, or "Unknown"
for IGR mutations.
* Regex: `[A-Za-z0-9]+`
* Synonyms: `Hugo_Symbol`, `Gene_name`
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