diff --git a/.github/sync-repo-settings.yaml b/.github/sync-repo-settings.yaml
index 1b362683..d1e8b5e6 100644
--- a/.github/sync-repo-settings.yaml
+++ b/.github/sync-repo-settings.yaml
@@ -9,9 +9,9 @@ branchProtectionRules:
       - "ci/kokoro: System test"
       - docs
       - lint
-      - test (10)
       - test (12)
       - test (14)
+      - test (16)
       - cla/google
       - windows
       - OwlBot Post Processor
diff --git a/.github/workflows/ci.yaml b/.github/workflows/ci.yaml
index 25251dbb..f447b84a 100644
--- a/.github/workflows/ci.yaml
+++ b/.github/workflows/ci.yaml
@@ -9,7 +9,7 @@ jobs:
     runs-on: ubuntu-latest
     strategy:
       matrix:
-        node: [10, 12, 14]
+        node: [12, 14, 16]
     steps:
       - uses: actions/checkout@v3
       - uses: actions/setup-node@v3
diff --git a/.kokoro/continuous/node10/common.cfg b/.kokoro/continuous/node10/common.cfg
deleted file mode 100644
index b14b3c95..00000000
--- a/.kokoro/continuous/node10/common.cfg
+++ /dev/null
@@ -1,34 +0,0 @@
-# Format: //devtools/kokoro/config/proto/build.proto
-
-# Build logs will be here
-action {
-  define_artifacts {
-    regex: "**/*sponge_log.xml"
-  }
-}
-
-# Bring in codecov.io token into the build as $KOKORO_KEYSTORE_DIR/73713_dpebot_codecov_token
-before_action {
-  fetch_keystore {
-    keystore_resource {
-      keystore_config_id: 73713
-      keyname: "dpebot_codecov_token"
-    }
-  }
-}
-
-# Download trampoline resources.
-gfile_resources: "/bigstore/cloud-devrel-kokoro-resources/trampoline"
-
-# Use the trampoline script to run in docker.
-build_file: "nodejs-ai-platform/.kokoro/trampoline_v2.sh"
-
-# Configure the docker image for kokoro-trampoline.
-env_vars: {
-    key: "TRAMPOLINE_IMAGE"
-    value: "gcr.io/cloud-devrel-kokoro-resources/node:10-user"
-}
-env_vars: {
-    key: "TRAMPOLINE_BUILD_FILE"
-    value: "github/nodejs-ai-platform/.kokoro/test.sh"
-}
diff --git a/.kokoro/continuous/node10/docs.cfg b/.kokoro/continuous/node10/docs.cfg
deleted file mode 100644
index 8a96bb9a..00000000
--- a/.kokoro/continuous/node10/docs.cfg
+++ /dev/null
@@ -1,4 +0,0 @@
-env_vars: {
-    key: "TRAMPOLINE_BUILD_FILE"
-    value: "github/nodejs-ai-platform/.kokoro/docs.sh"
-}
diff --git a/.kokoro/continuous/node10/test.cfg b/.kokoro/continuous/node10/test.cfg
deleted file mode 100644
index 609c0cf0..00000000
--- a/.kokoro/continuous/node10/test.cfg
+++ /dev/null
@@ -1,9 +0,0 @@
-# Bring in codecov.io token into the build as $KOKORO_KEYSTORE_DIR/73713_dpebot_codecov_token
-before_action {
-  fetch_keystore {
-    keystore_resource {
-      keystore_config_id: 73713
-      keyname: "dpebot_codecov_token"
-    }
-  }
-}
diff --git a/.kokoro/presubmit/node10/common.cfg b/.kokoro/presubmit/node10/common.cfg
deleted file mode 100644
index b14b3c95..00000000
--- a/.kokoro/presubmit/node10/common.cfg
+++ /dev/null
@@ -1,34 +0,0 @@
-# Format: //devtools/kokoro/config/proto/build.proto
-
-# Build logs will be here
-action {
-  define_artifacts {
-    regex: "**/*sponge_log.xml"
-  }
-}
-
-# Bring in codecov.io token into the build as $KOKORO_KEYSTORE_DIR/73713_dpebot_codecov_token
-before_action {
-  fetch_keystore {
-    keystore_resource {
-      keystore_config_id: 73713
-      keyname: "dpebot_codecov_token"
-    }
-  }
-}
-
-# Download trampoline resources.
-gfile_resources: "/bigstore/cloud-devrel-kokoro-resources/trampoline"
-
-# Use the trampoline script to run in docker.
-build_file: "nodejs-ai-platform/.kokoro/trampoline_v2.sh"
-
-# Configure the docker image for kokoro-trampoline.
-env_vars: {
-    key: "TRAMPOLINE_IMAGE"
-    value: "gcr.io/cloud-devrel-kokoro-resources/node:10-user"
-}
-env_vars: {
-    key: "TRAMPOLINE_BUILD_FILE"
-    value: "github/nodejs-ai-platform/.kokoro/test.sh"
-}
diff --git a/package.json b/package.json
index ecd70772..5203f828 100644
--- a/package.json
+++ b/package.json
@@ -47,7 +47,7 @@
     "test": "c8 node build/test/run.js"
   },
   "dependencies": {
-    "google-gax": "^2.24.1",
+    "google-gax": "^3.0.1",
     "protobuf.js": "^1.1.2"
   },
   "devDependencies": {
@@ -55,21 +55,21 @@
     "@types/node": "^16.0.0",
     "@types/sinon": "^10.0.0",
     "c8": "^7.3.5",
-    "gts": "^3.0.2",
+    "gts": "^3.1.0",
     "jsdoc": "^3.6.6",
     "jsdoc-fresh": "^1.0.2",
     "jsdoc-region-tag": "^1.0.6",
     "linkinator": "^2.2.2",
-    "mocha": "^8.2.1",
+    "mocha": "^9.2.2",
     "null-loader": "^4.0.1",
     "pack-n-play": "^1.0.0-2",
     "sinon": "^13.0.0",
     "ts-loader": "^9.0.0",
-    "typescript": "^4.0.5",
+    "typescript": "^4.6.4",
     "webpack": "^5.4.0",
     "webpack-cli": "^4.2.0"
   },
   "engines": {
-    "node": ">=10.0.0"
+    "node": ">=12.0.0"
   }
 }
diff --git a/samples/package.json b/samples/package.json
index 02501503..e1f6bfb9 100644
--- a/samples/package.json
+++ b/samples/package.json
@@ -4,7 +4,7 @@
   "license": "Apache-2.0",
   "author": "Google LLC",
   "engines": {
-    "node": ">=10"
+    "node": ">=12.0.0"
   },
   "files": [
     "*.js"