Laspy is a pythonic interface for reading/modifying/creating .LAS LIDAR files matching specification 1.0-1.4.
Python
Latest commit 4d0a877 Jun 30, 2016 @grantbrown committed on GitHub Merge pull request #50 from kbevers/write-faster
Removed unnecessary ndarray to list conversion. Speeds up writing significantly.

README.md

LAS-Read-Writer-in-Python

Laspy is a python library for reading, modifying and creating .LAS LIDAR files. It was designed for python 2.7

API Documentation and tutorials are available at http://pythonhosted.org/laspy. Installation is standard:

python setup.py build
python setup.py install 

You may need to run these commands as root/administrator.