diff --git a/README.md b/README.md
index e1f7bf59..1a1e96f3 100644
--- a/README.md
+++ b/README.md
@@ -173,6 +173,10 @@ The `graphqlHTTP` function accepts the following options:
 - **`formatError`**: is deprecated and replaced by `customFormatErrorFn`. It will be
   removed in version 1.0.0.
 
+- **`handleRuntimeQueryErrorFn`**: An optional function which can be used to change the status code
+  or headers of the response in case of a runtime query error. By default, the status code is set to
+  `500`.
+
 In addition to an object defining each option, options can also be provided as
 a function (or async function) which returns this options object. This function
 is provided the arguments `(request, response, graphQLParams)` and is called
diff --git a/src/__tests__/usage-test.ts b/src/__tests__/usage-test.ts
index d63ee572..9c7dce80 100644
--- a/src/__tests__/usage-test.ts
+++ b/src/__tests__/usage-test.ts
@@ -2,7 +2,12 @@ import express from 'express';
 import request from 'supertest';
 import { expect } from 'chai';
 import { describe, it } from 'mocha';
-import { GraphQLSchema } from 'graphql';
+import {
+  GraphQLNonNull,
+  GraphQLObjectType,
+  GraphQLSchema,
+  GraphQLString,
+} from 'graphql';
 
 import { graphqlHTTP } from '../index';
 
@@ -96,6 +101,40 @@ describe('Useful errors when incorrectly used', () => {
     });
   });
 
+  it('uses the custom runtime query error handling function', async () => {
+    const schema = new GraphQLSchema({
+      query: new GraphQLObjectType({
+        name: 'QueryRoot',
+        fields: {
+          test: {
+            type: new GraphQLNonNull(GraphQLString),
+            resolve() {
+              throw new Error('Throws!');
+            },
+          },
+        },
+      }),
+    });
+
+    const app = express();
+
+    app.use(
+      '/graphql',
+      graphqlHTTP({
+        handleRuntimeQueryErrorFn(_, response) {
+          response.setHeader('customRuntimeQueryError', "I'm a teapot");
+          response.statusCode = 418;
+        },
+        schema,
+      }),
+    );
+
+    const response = await request(app).get('/graphql?query={test}');
+
+    expect(response.status).to.equal(418);
+    expect(response.get('customRuntimeQueryError')).to.equal("I'm a teapot");
+  });
+
   it('validates schema before executing request', async () => {
     // @ts-expect-error
     const schema = new GraphQLSchema({ directives: [null] });
diff --git a/src/index.ts b/src/index.ts
index 10a74752..b04fdb06 100644
--- a/src/index.ts
+++ b/src/index.ts
@@ -115,6 +115,15 @@ export interface OptionsData {
    */
   formatError?: (error: GraphQLError) => GraphQLFormattedError;
 
+  /**
+   * Use this to modify the response when a runtime query error occurs. By
+   * default the statusCode will be set to 500.
+   */
+  handleRuntimeQueryErrorFn?: (
+    result: ExecutionResult,
+    response: Response,
+  ) => void;
+
   /**
    * An optional function for adding additional metadata to the GraphQL response
    * as a key-value object. The result will be added to "extensions" field in
@@ -200,6 +209,7 @@ export function graphqlHTTP(options: Options): Middleware {
     let formatErrorFn = formatError;
     let pretty = false;
     let result: ExecutionResult;
+    let optionsData: OptionsData | undefined;
 
     try {
       // Parse the Request to get GraphQL request parameters.
@@ -208,7 +218,7 @@ export function graphqlHTTP(options: Options): Middleware {
       } catch (error: unknown) {
         // When we failed to parse the GraphQL parameters, we still need to get
         // the options object, so make an options call to resolve just that.
-        const optionsData = await resolveOptions();
+        optionsData = await resolveOptions();
         pretty = optionsData.pretty ?? false;
         formatErrorFn =
           optionsData.customFormatErrorFn ??
@@ -218,7 +228,7 @@ export function graphqlHTTP(options: Options): Middleware {
       }
 
       // Then, resolve the Options to get OptionsData.
-      const optionsData: OptionsData = await resolveOptions(params);
+      optionsData = await resolveOptions(params);
 
       // Collect information from the options data object.
       const schema = optionsData.schema;
@@ -388,13 +398,22 @@ export function graphqlHTTP(options: Options): Middleware {
       }
     }
 
-    // If no data was included in the result, that indicates a runtime query
-    // error, indicate as such with a generic status code.
-    // Note: Information about the error itself will still be contained in
-    // the resulting JSON payload.
-    // https://graphql.github.io/graphql-spec/#sec-Data
-    if (response.statusCode === 200 && result.data == null) {
-      response.statusCode = 500;
+    if (result.errors != null || result.data == null) {
+      const handleRuntimeQueryErrorFn =
+        optionsData?.handleRuntimeQueryErrorFn ??
+        ((_result, _response) => {
+          // If no data was included in the result, that indicates a runtime query
+          // error, indicate as such with a generic status code.
+          // Note: Information about the error itself will still be contained in
+          // the resulting JSON payload.
+          // https://graphql.github.io/graphql-spec/#sec-Data
+
+          if (_response.statusCode === 200 && _result.data == null) {
+            _response.statusCode = 500;
+          }
+        });
+
+      handleRuntimeQueryErrorFn(result, response);
     }
 
     // Format any encountered errors.