pVACtools is a cancer immunotherapy tools suite consisting of the following tools:
A cancer immunotherapy pipeline for identifying and prioritizing neoantigens from a list of tumor mutations.
A tool for detecting neoantigens resulting from gene fusions.
A tool designed to aid specifically in the construction of DNA-based cancer vaccines.
A browser-based user interface that assists users in launching, managing, reviewing, and visualizing the results of pVACtools processes.
The pVACapi provides a HTTP REST interface to the pVACtools suite..
Jasreet Hundal, Beatriz M. Carreno, Allegra A. Petti, Gerald P. Linette, Obi L. Griffith, Elaine R. Mardis, and Malachi Griffith. pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens. Genome Medicine. 2016, 8:11, DOI: 10.1186/s13073-016-0264-5. PMID: 26825632.
This project is licensed under NPOSL-3.0.
We're currently in the process of preparing pVACtools for packaging. Once finished, pVACtools will be available on PyPi and available for install using
For the time being pVACseq is still available as a standalone package and can be installed using
pip install pvacseq. The original pVACseq documentation can be found on readthedocs.