diff --git a/packages/grpc-native-core/binding.gyp b/packages/grpc-native-core/binding.gyp
index f1fc3dd66..c27050242 100644
--- a/packages/grpc-native-core/binding.gyp
+++ b/packages/grpc-native-core/binding.gyp
@@ -91,7 +91,7 @@
       'GPR_BACKWARDS_COMPATIBILITY_MODE',
       'GRPC_ARES=0',
       'GRPC_UV',
-      'GRPC_NODE_VERSION="1.20.3"'
+      'GRPC_NODE_VERSION="1.22.0-dev"'
     ],
     'defines!': [
       'OPENSSL_THREADS'
@@ -569,7 +569,6 @@
       ],
       'sources': [
         'deps/grpc/src/core/lib/gpr/alloc.cc',
-        'deps/grpc/src/core/lib/gpr/arena.cc',
         'deps/grpc/src/core/lib/gpr/atm.cc',
         'deps/grpc/src/core/lib/gpr/cpu_iphone.cc',
         'deps/grpc/src/core/lib/gpr/cpu_linux.cc',
@@ -602,7 +601,9 @@
         'deps/grpc/src/core/lib/gpr/tmpfile_posix.cc',
         'deps/grpc/src/core/lib/gpr/tmpfile_windows.cc',
         'deps/grpc/src/core/lib/gpr/wrap_memcpy.cc',
+        'deps/grpc/src/core/lib/gprpp/arena.cc',
         'deps/grpc/src/core/lib/gprpp/fork.cc',
+        'deps/grpc/src/core/lib/gprpp/global_config_env.cc',
         'deps/grpc/src/core/lib/gprpp/thd_posix.cc',
         'deps/grpc/src/core/lib/gprpp/thd_windows.cc',
         'deps/grpc/src/core/lib/profiling/basic_timers.cc',
@@ -638,6 +639,7 @@
         'deps/grpc/src/core/lib/channel/handshaker_registry.cc',
         'deps/grpc/src/core/lib/channel/status_util.cc',
         'deps/grpc/src/core/lib/compression/compression.cc',
+        'deps/grpc/src/core/lib/compression/compression_args.cc',
         'deps/grpc/src/core/lib/compression/compression_internal.cc',
         'deps/grpc/src/core/lib/compression/message_compress.cc',
         'deps/grpc/src/core/lib/compression/stream_compression.cc',
@@ -650,12 +652,15 @@
         'deps/grpc/src/core/lib/http/parser.cc',
         'deps/grpc/src/core/lib/iomgr/buffer_list.cc',
         'deps/grpc/src/core/lib/iomgr/call_combiner.cc',
+        'deps/grpc/src/core/lib/iomgr/cfstream_handle.cc',
         'deps/grpc/src/core/lib/iomgr/combiner.cc',
         'deps/grpc/src/core/lib/iomgr/endpoint.cc',
+        'deps/grpc/src/core/lib/iomgr/endpoint_cfstream.cc',
         'deps/grpc/src/core/lib/iomgr/endpoint_pair_posix.cc',
         'deps/grpc/src/core/lib/iomgr/endpoint_pair_uv.cc',
         'deps/grpc/src/core/lib/iomgr/endpoint_pair_windows.cc',
         'deps/grpc/src/core/lib/iomgr/error.cc',
+        'deps/grpc/src/core/lib/iomgr/error_cfstream.cc',
         'deps/grpc/src/core/lib/iomgr/ev_epoll1_linux.cc',
         'deps/grpc/src/core/lib/iomgr/ev_epollex_linux.cc',
         'deps/grpc/src/core/lib/iomgr/ev_poll_posix.cc',
@@ -676,6 +681,7 @@
         'deps/grpc/src/core/lib/iomgr/iomgr_custom.cc',
         'deps/grpc/src/core/lib/iomgr/iomgr_internal.cc',
         'deps/grpc/src/core/lib/iomgr/iomgr_posix.cc',
+        'deps/grpc/src/core/lib/iomgr/iomgr_posix_cfstream.cc',
         'deps/grpc/src/core/lib/iomgr/iomgr_uv.cc',
         'deps/grpc/src/core/lib/iomgr/iomgr_windows.cc',
         'deps/grpc/src/core/lib/iomgr/is_epollexclusive_available.cc',
@@ -704,6 +710,7 @@
         'deps/grpc/src/core/lib/iomgr/socket_utils_windows.cc',
         'deps/grpc/src/core/lib/iomgr/socket_windows.cc',
         'deps/grpc/src/core/lib/iomgr/tcp_client.cc',
+        'deps/grpc/src/core/lib/iomgr/tcp_client_cfstream.cc',
         'deps/grpc/src/core/lib/iomgr/tcp_client_custom.cc',
         'deps/grpc/src/core/lib/iomgr/tcp_client_posix.cc',
         'deps/grpc/src/core/lib/iomgr/tcp_client_windows.cc',
@@ -937,12 +944,15 @@
         'deps/grpc/src/core/ext/filters/client_channel/lb_policy/round_robin/round_robin.cc',
         'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/c_ares/dns_resolver_ares.cc',
         'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/c_ares/grpc_ares_ev_driver.cc',
+        'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/c_ares/grpc_ares_ev_driver_libuv.cc',
         'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/c_ares/grpc_ares_ev_driver_posix.cc',
         'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/c_ares/grpc_ares_ev_driver_windows.cc',
         'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/c_ares/grpc_ares_wrapper.cc',
         'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/c_ares/grpc_ares_wrapper_fallback.cc',
+        'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/c_ares/grpc_ares_wrapper_libuv.cc',
         'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/c_ares/grpc_ares_wrapper_posix.cc',
         'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/c_ares/grpc_ares_wrapper_windows.cc',
+        'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/dns_resolver_selection.cc',
         'deps/grpc/src/core/ext/filters/client_channel/resolver/dns/native/dns_resolver.cc',
         'deps/grpc/src/core/ext/filters/client_channel/resolver/sockaddr/sockaddr_resolver.cc',
         'deps/grpc/src/core/ext/filters/census/grpc_context.cc',
diff --git a/packages/grpc-native-core/build.yaml b/packages/grpc-native-core/build.yaml
index 74cb99d9d..49e36fdfe 100644
--- a/packages/grpc-native-core/build.yaml
+++ b/packages/grpc-native-core/build.yaml
@@ -1,3 +1,2 @@
 settings:
   '#': It's possible to have node_version here as a key to override the core's version.
-  node_version: 1.20.3
diff --git a/packages/grpc-native-core/deps/grpc b/packages/grpc-native-core/deps/grpc
index cb0129702..bb6a97b0c 160000
--- a/packages/grpc-native-core/deps/grpc
+++ b/packages/grpc-native-core/deps/grpc
@@ -1 +1 @@
-Subproject commit cb012970215b8c5141f4fdfdbe850006bd7994d6
+Subproject commit bb6a97b0c8fc11a5c27b03e2058dc383bbfc1e64
diff --git a/packages/grpc-native-core/package.json b/packages/grpc-native-core/package.json
index 9a1a22c75..ea3e05ed6 100644
--- a/packages/grpc-native-core/package.json
+++ b/packages/grpc-native-core/package.json
@@ -1,6 +1,6 @@
 {
   "name": "grpc",
-  "version": "1.20.3",
+  "version": "1.22.0-dev",
   "author": "Google Inc.",
   "description": "gRPC Library for Node",
   "homepage": "https://grpc.io/",