diff --git a/CMakeLists.txt b/CMakeLists.txt
index 605b2675f1b64..4feb82ff4bb3f 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -63,6 +63,8 @@ set(CMAKE_POSITION_INDEPENDENT_CODE ON)
 include(CheckSourceCompilesAndLinks)
 include(cmake/introspection.cmake)
 
+include(cmake/crc32c.cmake)
+
 add_subdirectory(src)
 
 message("\n")
diff --git a/cmake/crc32c.cmake b/cmake/crc32c.cmake
new file mode 100644
index 0000000000000..fa3e629dc1d0b
--- /dev/null
+++ b/cmake/crc32c.cmake
@@ -0,0 +1,113 @@
+# Copyright (c) 2023 The Bitcoin Core developers
+# Distributed under the MIT software license, see the accompanying
+# file COPYING or http://www.opensource.org/licenses/mit-license.php.
+
+# This file is part of the transition from Autotools to CMake. Once CMake
+# support has been merged we should switch to using the upstream CMake
+# buildsystem.
+
+include(CheckCXXSourceCompiles)
+
+# Check for __builtin_prefetch support in the compiler.
+check_cxx_source_compiles("
+  int main() {
+    char data = 0;
+    const char* address = &data;
+    __builtin_prefetch(address, 0, 0);
+    return 0;
+  }
+  " HAVE_BUILTIN_PREFETCH
+)
+
+# Check for _mm_prefetch support in the compiler.
+check_cxx_source_compiles("
+  #if defined(_MSC_VER)
+  #include <intrin.h>
+  #else
+  #include <xmmintrin.h>
+  #endif
+
+  int main() {
+    char data = 0;
+    const char* address = &data;
+    _mm_prefetch(address, _MM_HINT_NTA);
+    return 0;
+  }
+  " HAVE_MM_PREFETCH
+)
+
+# Check for SSE4.2 support in the compiler.
+if(MSVC)
+  set(SSE42_CXXFLAGS /arch:AVX)
+else()
+  set(SSE42_CXXFLAGS -msse4.2)
+endif()
+check_cxx_source_compiles_with_flags("${SSE42_CXXFLAGS}" "
+  #include <cstdint>
+  #if defined(_MSC_VER)
+  #include <intrin.h>
+  #elif defined(__GNUC__) && defined(__SSE4_2__)
+  #include <nmmintrin.h>
+  #endif
+
+  int main() {
+    uint64_t l = 0;
+    l = _mm_crc32_u8(l, 0);
+    l = _mm_crc32_u32(l, 0);
+    l = _mm_crc32_u64(l, 0);
+    return l;
+  }
+  " HAVE_SSE42
+)
+
+# Check for ARMv8 w/ CRC and CRYPTO extensions support in the compiler.
+set(ARM_CRC_CXXFLAGS -march=armv8-a+crc)
+check_cxx_source_compiles_with_flags("${ARM_CRC_CXXFLAGS}" "
+  #include <arm_acle.h>
+  #include <arm_neon.h>
+
+  int main() {
+  #ifdef __aarch64__
+    __crc32cb(0, 0); __crc32ch(0, 0); __crc32cw(0, 0); __crc32cd(0, 0);
+    vmull_p64(0, 0);
+  #else
+  #error crc32c library does not support hardware acceleration on 32-bit ARM
+  #endif
+    return 0;
+  }
+  " HAVE_ARM64_CRC32C
+)
+
+add_library(crc32c STATIC EXCLUDE_FROM_ALL
+  ${PROJECT_SOURCE_DIR}/src/crc32c/src/crc32c.cc
+  ${PROJECT_SOURCE_DIR}/src/crc32c/src/crc32c_portable.cc
+)
+
+target_compile_definitions(crc32c
+  PRIVATE
+    HAVE_BUILTIN_PREFETCH=$<BOOL:${HAVE_BUILTIN_PREFETCH}>
+    HAVE_MM_PREFETCH=$<BOOL:${HAVE_MM_PREFETCH}>
+    HAVE_STRONG_GETAUXVAL=$<BOOL:${HAVE_STRONG_GETAUXVAL}>
+    HAVE_SSE42=$<BOOL:${HAVE_SSE42}>
+    HAVE_ARM64_CRC32C=$<BOOL:${HAVE_ARM64_CRC32C}>
+    BYTE_ORDER_BIG_ENDIAN=${WORDS_BIGENDIAN}
+)
+
+target_include_directories(crc32c
+  PUBLIC
+    $<BUILD_INTERFACE:${PROJECT_SOURCE_DIR}/src/crc32c/include>
+)
+
+if(HAVE_SSE42)
+  target_sources(crc32c PRIVATE ${PROJECT_SOURCE_DIR}/src/crc32c/src/crc32c_sse42.cc)
+  set_property(SOURCE ${PROJECT_SOURCE_DIR}/src/crc32c/src/crc32c_sse42.cc
+    APPEND PROPERTY COMPILE_OPTIONS ${SSE42_CXXFLAGS}
+  )
+endif()
+
+if(HAVE_ARM64_CRC32C)
+  target_sources(crc32c PRIVATE ${PROJECT_SOURCE_DIR}/src/crc32c/src/crc32c_arm64.cc)
+  set_property(SOURCE ${PROJECT_SOURCE_DIR}/src/crc32c/src/crc32c_arm64.cc
+    APPEND PROPERTY COMPILE_OPTIONS ${ARM_CRC_CXXFLAGS}
+  )
+endif()