diff --git a/CMakeLists.txt b/CMakeLists.txt
index 95df5055fc4a4..4b9f0c8bf26b8 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -84,6 +84,8 @@ set(configure_warnings)
 # It is intended to be a usage requirement for all other targets.
 add_library(core INTERFACE)
 
+include(TryAppendLinkerFlag)
+
 if(WIN32)
   #[=[
   This build system supports two ways to build binaries for Windows.
@@ -126,14 +128,29 @@ if(WIN32)
       _MT
     )
     # We require Windows 7 (NT 6.1) or later.
-    add_link_options(-Wl,--major-subsystem-version,6 -Wl,--minor-subsystem-version,1)
+    try_append_linker_flag(core "-Wl,--major-subsystem-version,6")
+    try_append_linker_flag(core "-Wl,--minor-subsystem-version,1")
   endif()
 endif()
 
+# Use 64-bit off_t on 32-bit Linux.
+if (CMAKE_SYSTEM_NAME STREQUAL "Linux" AND CMAKE_SIZEOF_VOID_P EQUAL 4)
+  # Ensure 64-bit offsets are used for filesystem accesses for 32-bit compilation.
+  target_compile_definitions(core INTERFACE
+    _FILE_OFFSET_BITS=64
+  )
+endif()
+
 if(CMAKE_SYSTEM_NAME STREQUAL "Darwin")
   target_compile_definitions(core INTERFACE
     MAC_OSX
   )
+  # These flags are specific to ld64, and may cause issues with other linkers.
+  # For example: GNU ld will interpret -dead_strip as -de and then try and use
+  # "ad_strip" as the symbol for the entry point.
+  try_append_linker_flag(core "-Wl,-dead_strip")
+  try_append_linker_flag(core "-Wl,-dead_strip_dylibs")
+  try_append_linker_flag(core "-Wl,-headerpad_max_install_names")
 endif()
 
 if(CMAKE_CROSSCOMPILING AND DEPENDS_ALLOW_HOST_PACKAGES)
@@ -230,6 +247,8 @@ else()
   set(common_link_options)
 endif()
 message("Common link options ................... ${common_link_options}")
+message("Linker flags for executables .......... ${CMAKE_EXE_LINKER_FLAGS}")
+message("Linker flags for shared libraries ..... ${CMAKE_SHARED_LINKER_FLAGS}")
 if(DEFINED CMAKE_BUILD_TYPE)
   message("Build type:")
   message(" - CMAKE_BUILD_TYPE ................... ${CMAKE_BUILD_TYPE}")
diff --git a/depends/toolchain.cmake.in b/depends/toolchain.cmake.in
index 59c98d745209d..c64ac90e8fc9c 100644
--- a/depends/toolchain.cmake.in
+++ b/depends/toolchain.cmake.in
@@ -73,6 +73,10 @@ if(NOT CMAKE_OBJCXX_COMPILER)
 endif()
 set(CMAKE_OBJCXX_FLAGS_INIT "${DEPENDS_OBJCXX_COMPILER_FLAGS} @CPPFLAGS@ @CXXFLAGS@")
 
+if(CMAKE_SYSTEM_NAME STREQUAL "Windows")
+  set(CMAKE_EXE_LINKER_FLAGS_INIT "-static")
+endif()
+
 set(CMAKE_AR "@AR@")
 set(CMAKE_RANLIB "@RANLIB@")
 set(CMAKE_STRIP "@STRIP@")
diff --git a/src/CMakeLists.txt b/src/CMakeLists.txt
index ff499979078b3..84593f72bfb68 100644
--- a/src/CMakeLists.txt
+++ b/src/CMakeLists.txt
@@ -243,10 +243,6 @@ if(BUILD_DAEMON)
       core
       bitcoin_node
   )
-  target_link_options(bitcoind
-    PRIVATE
-      $<$<BOOL:${MINGW}>:-static>
-  )
 endif()