R package: OMiAT
Title: Optimal Microbiome-based Association Test (OMiAT)
Author: Hyunwook Koh, Martin J. Blaser, and Huilin Li
Maintainer: Hyunwook Koh email@example.com
Description: This software package provides facilities for 1) optimal microbiome-based association test (OMiAT) which tests the association for microbial community composition and 2) microbiome comprehensive association mapping (MiCAM) which tests the association for microbial composition in all different microbial taxa through a breadth of taxonomic levels (e.g., kingdom, phylum, class, order, family, genus and species). Continuous or binary traits (for either human health/disease outcomes or medical interventions) can be surveyed with/without covariate adjustments (e.g., age, sex).
Depends: R(>= 3.2.3)
Imports: ape, BiasedUrn, cluster, CompQuadForm, dirmult, dummies, ecodist, GUniFrac, phangorn, phyloseq, robustbase, robCompositions
Koh H, Blaser MJ, Li H. (2017) A powerful microbiome-based association test and a microbial taxa discovery framework for comprehensive association mapping. Microbiome 5:45.
library(devtools) install_github("hk1785/OMiAT", force=T)