diff --git a/internal/i18n/en_translations.go b/internal/i18n/en_translations.go
index 9905330683..681c226848 100644
--- a/internal/i18n/en_translations.go
+++ b/internal/i18n/en_translations.go
@@ -205,4 +205,5 @@ var (
 	MsgInvalidIdentity             = ffm("FF10285", "Supplied Fabric signer identity is invalid", 400)
 	MsgFailedToDecodeCertificate   = ffm("FF10286", "Failed to decode certificate: %s", 500)
 	MsgInvalidMessageType          = ffm("FF10287", "Invalid message type - allowed types are %s", 400)
+	MsgNoUUID                      = ffm("FF10288", "Field '%s' must not be a UUID", 400)
 )
diff --git a/pkg/fftypes/validations.go b/pkg/fftypes/validations.go
index 4aede21f1b..a895ac0f6e 100644
--- a/pkg/fftypes/validations.go
+++ b/pkg/fftypes/validations.go
@@ -31,6 +31,10 @@ func ValidateFFNameField(ctx context.Context, str string, fieldName string) erro
 	if !ffNameValidator.MatchString(str) {
 		return i18n.NewError(ctx, i18n.MsgInvalidName, fieldName)
 	}
+	if _, err := ParseUUID(ctx, str); err == nil {
+		// Name must not be a UUID
+		return i18n.NewError(ctx, i18n.MsgNoUUID, fieldName)
+	}
 	return nil
 }
 
diff --git a/pkg/fftypes/validations_test.go b/pkg/fftypes/validations_test.go
index 6236b71e08..8d4c035e91 100644
--- a/pkg/fftypes/validations_test.go
+++ b/pkg/fftypes/validations_test.go
@@ -37,6 +37,9 @@ func TestValidateFFNameField(t *testing.T) {
 	err = ValidateFFNameField(context.Background(), "0123456789_123456789-123456789.123456789-123456789_12345678901234", "badField")
 	assert.Regexp(t, "FF10131.*badField", err)
 
+	err = ValidateFFNameField(context.Background(), "af34658e-a728-4b21-b9cf-8451f07be065", "badField")
+	assert.Regexp(t, "FF10288.*badField", err)
+
 }
 
 func TestValidateLength(t *testing.T) {