diff --git a/Lib/test/test_compile.py b/Lib/test/test_compile.py
index f681d125db7d7a..65c76a046cf238 100644
--- a/Lib/test/test_compile.py
+++ b/Lib/test/test_compile.py
@@ -444,6 +444,10 @@ def f():
         self.assertIn("_A__mangled_mod", A.f.__code__.co_varnames)
         self.assertIn("__package__", A.f.__code__.co_varnames)
 
+    def test_condition_expression_with_dead_blocks_compiles(self):
+        # See gh-113054
+        compile('if 5 if 5 else T:y', '<eval>', 'exec')
+
     def test_compile_invalid_namedexpr(self):
         # gh-109351
         m = ast.Module(
diff --git a/Misc/NEWS.d/next/Core and Builtins/2023-12-14-20-08-35.gh-issue-113054.e20CtM.rst b/Misc/NEWS.d/next/Core and Builtins/2023-12-14-20-08-35.gh-issue-113054.e20CtM.rst
new file mode 100644
index 00000000000000..fea2eaeb30106a
--- /dev/null
+++ b/Misc/NEWS.d/next/Core and Builtins/2023-12-14-20-08-35.gh-issue-113054.e20CtM.rst	
@@ -0,0 +1,2 @@
+Fixed bug where a redindant NOP is not removed, causing an assertion to fail
+in the compiler in debug mode.
diff --git a/Python/flowgraph.c b/Python/flowgraph.c
index fe632082d5a66c..86f439fe324f6e 100644
--- a/Python/flowgraph.c
+++ b/Python/flowgraph.c
@@ -1110,7 +1110,10 @@ remove_redundant_jumps(cfg_builder *g) {
      * of that jump. If it is, then the jump instruction is redundant and
      * can be deleted.
      */
+
     assert(no_empty_basic_blocks(g));
+
+    bool remove_empty_blocks = false;
     for (basicblock *b = g->g_entryblock; b != NULL; b = b->b_next) {
         cfg_instr *last = basicblock_last_instr(b);
         assert(last != NULL);
@@ -1123,9 +1126,19 @@ remove_redundant_jumps(cfg_builder *g) {
             if (last->i_target == b->b_next) {
                 assert(b->b_next->b_iused);
                 INSTR_SET_OP0(last, NOP);
+                if (last->i_loc.lineno == NO_LOCATION.lineno) {
+                    b->b_iused--;
+                    if (b->b_iused == 0) {
+                        remove_empty_blocks = true;
+                    }
+                }
             }
         }
     }
+    if (remove_empty_blocks) {
+        eliminate_empty_basic_blocks(g);
+    }
+    assert(no_empty_basic_blocks(g));
     return SUCCESS;
 }