As of 5.3, Cyberduck is no longer able to properly read details when multiple Cloudfront distributions are in use. The same details are shown for all distributions, and these details seem to reflect the first distribution (based on alphabetical list) and no invalidations can be initiated.
Invalidations and most details are now working in the latest snapshot, however the invalidation counter still seems to be broken. For distributions with validation counts over 100 it just lists 100. For smaller counts it seems to work fine.
Using the latest 220.127.116.1178 build, I'm now receiving a rate error when attempting to access Cloudfront details distributions with large numbers of historic validations. Unlike previous snapshots, I am no longer able to submit invalidations.