Protein residue conservation, mapping on the structure, clustering of conserved residues - main scoring engine in Cube server.
C Java Perl Makefile
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00_include
01_data_structures
02_parsers
03_output
04_residue_scoring
05_cluster_scoring
06_main
07_utils
08_data
09_tools
10_objects
11_tests
.gitignore
README
README.md
copyright
license.md

README.md

Specs

Intro

Specs code implements several heuristic methods for detection of conserved regions on protein sequence and structure. The purpose of such an exercise is, typically, to help in the rational design of single-site mutational experiments, to estimate the impact of SNPs - inherited or arising in cancerous cells, or to guide computational docking.

To see the code at work on precompiled vertebrate sequences check out CubeDB server. To try it on your own set of seqeunces you can visit Cube server. To compile an run locally, read on.

Compilation

See the original README file.