Authors: Nathaniel J. Glasser, MD; Jacob C. Jameson, MS; Elbert S. Huang, MD; Ian M. Kronish, MD; Stacy Tessler Lindau, MD,; Monica Peek, MD; Elizabeth L. Tung, MD; Harold A. Pollack, PhD
Keywords: Gender, Masculinity, Identity, Cardiovascular Disease, Risk Reduction, Disease Prevention, Chronic Disease, Management, Social Determinants of Health
Question: What is the association of male gender expressivity (MGE) – a measure reflecting sociocultural pressures to convey male gender identity – with diagnosis and treatment of modifiable cardiovascular disease risks?
Findings: This cohort study involving 4,230 male participants found elevations in adolescent MGE were significantly associated with an 11% lower probability of adult hypertension treatment and a 15% lower probability of adult diabetes diagnoses. Elevations in young adult MGE were associated with lower probabilities of adult hypertension diagnoses, hypertension treatment, and diabetes treatment.
Meaning: Sociocultural pressures to convey male gender may lead to worse cardiovascular disease outcomes through associations with decreased diagnosis and treatment of modifiable risks.
This project utilizes renv for R dependency management to ensure reproducibility. renv captures the exact versions of R packages used, enabling consistent execution of scripts across different environments.
Execute source("run_all.R") to run the analyses. Outputs are generated in the outputs directory.
For issues related to project setup or execution, contact Jacob Jameson at jacobjameson@g.harvard.edu.

