A Bayesian framework for the analysis and interpretation of rare genetic variants
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BayesianModel_deposit.R
GenePriors.txt
LQTS_variants.txt
PredictionSets.tar.gz
README.md
Ruklisa_AdditionalData2_HierModelLQTSFull.bug
transcriptTable.txt

README.md

APPRAISE

A Bayesian framework for the analysis and interpretation of rare genetic variants

This repository contains data and scripts in order to reproduce the analyses described in:

Ruklisa D, Ware JS, Walsh R, Balding DJ, Cook SA. Bayesian models for syndrome- and gene-specific probabilities of novel variant pathogenicity. Genome Medicine. 2015;7:5.

http://genomemedicine.com/content/7/1/5