Pyneal - Real-time fMRI software
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License: MIT Build Status

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Pyneal -- real-time fMRI Analysis Software

Pyneal is an open source software package to support real-time functional magnetic resonance imaging (fMRI). It is entirely Python-based and depends exclusively on free, open source neuroimaging libraries.

It allows users to:

  • access functional MRI data in real-time
  • compute on-going analyses throughout a scan
  • monitor data quality
  • share analysis results with remote devices (e.g. send results to an experimental task presenting neurofeedback to participants)

It currently supports data formats used across 3 major MRI manufacturers: GE, Siemens, Philips.

In addition to allowing users to compute basic, ROI-based analyses during a scan, Pyneal also provides a simple framework for designing and writing customized analyses that can be computed across the whole brain volume at each timepoint.


Please see Pyneal Docs for full documentation of this package, including:

  • Overview
  • Installation/Setup
  • Usage
  • Customizing analyses
  • Simulating fMRI environments for testing
  • Troubleshooting


Pyneal is licensed under an MIT license. See the LICENSE file for additional details.


Please note that this project is released with a Contributor Code of Conduct. By contributing to this project you agree to abide by its terms.


Made possible through funding support by:

  • W.M. Keck Foundation; awarded to Andrea Stocco, PhD, Chantel Prat, PhD, & Rajesh Rao, PhD

  • NIMH R01 MH094743, Alfred P. Sloan Fellowship, Klingenstein Fellowship Award in the Neurosciences, Dana Foundation Brain and Immuno-Imaging Program; awarded to R. Alison Adcock, MD, PhD