diff --git a/.github/workflows/docker-build-push-master.yml b/.github/workflows/docker-build-push-master.yml
index de0433102..8437efd88 100644
--- a/.github/workflows/docker-build-push-master.yml
+++ b/.github/workflows/docker-build-push-master.yml
@@ -25,6 +25,9 @@ jobs:
   
       - name: Build latest-arm64v8
         run: docker build -t ${REPOSITORY}:latest-arm64v8 -f deployments/Dockerfile.arm64 .
+
+      - name: Build latest-s390x
+        run: docker build -t ${REPOSITORY}:latest-s390x -f deployments/Dockerfile.s390x .
   
       - name: Build latest-origin
         run: docker build -t ${REPOSITORY}:latest-origin -f deployments/Dockerfile.openshift .
@@ -34,6 +37,7 @@ jobs:
           docker tag ${REPOSITORY}:latest-amd64 ${REPOSITORY}:snapshot-amd64
           docker tag ${REPOSITORY}:latest-ppc64le ${REPOSITORY}:snapshot-ppc64le
           docker tag ${REPOSITORY}:latest-arm64v8 ${REPOSITORY}:snapshot-arm64v8
+          docker tag ${REPOSITORY}:latest-s390x ${REPOSITORY}:snapshot-s390x
 
       - name: Login to registry
         if: github.repository == 'intel/multus-cni'
@@ -45,20 +49,24 @@ jobs:
           docker push ${REPOSITORY}:latest-amd64
           docker push ${REPOSITORY}:latest-ppc64le
           docker push ${REPOSITORY}:latest-arm64v8
+          docker push ${REPOSITORY}:latest-s390x
           docker push ${REPOSITORY}:snapshot-amd64
           docker push ${REPOSITORY}:snapshot-ppc64le
           docker push ${REPOSITORY}:snapshot-arm64v8
+          docker push ${REPOSITORY}:snapshot-s390x
   
       - name: Create manifest for multi-arch images
         if: github.repository == 'intel/multus-cni'
         run: |
-          docker manifest create ${REPOSITORY}:snapshot ${REPOSITORY}:snapshot-amd64 ${REPOSITORY}:snapshot-ppc64le ${REPOSITORY}:snapshot-arm64v8
+          docker manifest create ${REPOSITORY}:snapshot ${REPOSITORY}:snapshot-amd64 ${REPOSITORY}:snapshot-ppc64le ${REPOSITORY}:snapshot-arm64v8 ${REPOSITORY}:snapshot-s390x
           docker manifest annotate ${REPOSITORY}:snapshot ${REPOSITORY}:snapshot-amd64 --arch amd64
           docker manifest annotate ${REPOSITORY}:snapshot ${REPOSITORY}:snapshot-ppc64le --arch ppc64le
           docker manifest annotate ${REPOSITORY}:snapshot ${REPOSITORY}:snapshot-arm64v8 --arch arm64
+          docker manifest annotate ${REPOSITORY}:snapshot ${REPOSITORY}:snapshot-s390x --arch s390x
           docker manifest push ${REPOSITORY}:snapshot
-          docker manifest create ${REPOSITORY}:latest ${REPOSITORY}:latest-amd64 ${REPOSITORY}:latest-ppc64le ${REPOSITORY}:latest-arm64v8
+          docker manifest create ${REPOSITORY}:latest ${REPOSITORY}:latest-amd64 ${REPOSITORY}:latest-ppc64le ${REPOSITORY}:latest-arm64v8 ${REPOSITORY}:latest-s390x
           docker manifest annotate ${REPOSITORY}:latest ${REPOSITORY}:latest-amd64 --arch amd64
           docker manifest annotate ${REPOSITORY}:latest ${REPOSITORY}:latest-ppc64le --arch ppc64le
           docker manifest annotate ${REPOSITORY}:latest ${REPOSITORY}:latest-arm64v8 --arch arm64
+          docker manifest annotate ${REPOSITORY}:latest ${REPOSITORY}:latest-s390x --arch s390x
           docker manifest push ${REPOSITORY}:latest
diff --git a/.github/workflows/docker-build-push-release.yml b/.github/workflows/docker-build-push-release.yml
index e0ba6bd8c..61f0c8d29 100644
--- a/.github/workflows/docker-build-push-release.yml
+++ b/.github/workflows/docker-build-push-release.yml
@@ -26,6 +26,9 @@ jobs:
       - name: Build latest-arm64v8
         run: docker build -t ${REPOSITORY}:latest-arm64v8 -f deployments/Dockerfile.arm64 .
   
+      - name: Build latest-s390x
+        run: docker build -t ${REPOSITORY}:latest-s390x -f deployments/Dockerfile.s390x .
+
       - name: Build latest-origin
         run: docker build -t ${REPOSITORY}:latest-origin -f deployments/Dockerfile.openshift .
   
@@ -34,9 +37,11 @@ jobs:
           docker tag ${REPOSITORY}:latest-amd64 ${REPOSITORY}:stable-amd64
           docker tag ${REPOSITORY}:latest-ppc64le ${REPOSITORY}:stable-ppc64le
           docker tag ${REPOSITORY}:latest-arm64v8 ${REPOSITORY}:stable-arm64v8
+          docker tag ${REPOSITORY}:latest-s390x ${REPOSITORY}:stable-s390x
           docker tag ${REPOSITORY}:latest-amd64 ${REPOSITORY}:${GITHUB_REF##*/}-amd64
           docker tag ${REPOSITORY}:latest-ppc64le ${REPOSITORY}:${GITHUB_REF##*/}-ppc64le
           docker tag ${REPOSITORY}:latest-arm64v8 ${REPOSITORY}:${GITHUB_REF##*/}-arm64v8
+          docker tag ${REPOSITORY}:latest-s390x ${REPOSITORY}:${GITHUB_REF##*/}-s390x
   
       - name: Login to registry
         if: github.repository == 'intel/multus-cni'
@@ -48,28 +53,34 @@ jobs:
           docker push ${REPOSITORY}:latest-amd64
           docker push ${REPOSITORY}:latest-ppc64le
           docker push ${REPOSITORY}:latest-arm64v8
+          docker push ${REPOSITORY}:latest-s390x
           docker push ${REPOSITORY}:stable-amd64
           docker push ${REPOSITORY}:stable-ppc64le
           docker push ${REPOSITORY}:stable-arm64v8
+          docker push ${REPOSITORY}:stable-s390x
           docker push ${REPOSITORY}:${GITHUB_REF##*/}-amd64
           docker push ${REPOSITORY}:${GITHUB_REF##*/}-ppc64le
           docker push ${REPOSITORY}:${GITHUB_REF##*/}-arm64v8
+          docker push ${REPOSITORY}:${GITHUB_REF##*/}-s390x
   
       - name: Create manifest for multi-arch images
         if: github.repository == 'intel/multus-cni'
         run: |
-          docker manifest create ${REPOSITORY}:stable ${REPOSITORY}:stable-amd64 ${REPOSITORY}:stable-ppc64le ${REPOSITORY}:stable-arm64v8
+          docker manifest create ${REPOSITORY}:stable ${REPOSITORY}:stable-amd64 ${REPOSITORY}:stable-ppc64le ${REPOSITORY}:stable-arm64v8 ${REPOSITORY}:stable-s390x
           docker manifest annotate ${REPOSITORY}:stable ${REPOSITORY}:stable-amd64 --arch amd64
           docker manifest annotate ${REPOSITORY}:stable ${REPOSITORY}:stable-ppc64le --arch ppc64le
           docker manifest annotate ${REPOSITORY}:stable ${REPOSITORY}:stable-arm64v8 --arch arm64
+          docker manifest annotate ${REPOSITORY}:stable ${REPOSITORY}:stable-s390x --arch s390x
           docker manifest push ${REPOSITORY}:stable
-          docker manifest create ${REPOSITORY}:latest ${REPOSITORY}:latest-amd64 ${REPOSITORY}:latest-ppc64le ${REPOSITORY}:latest-arm64v8
+          docker manifest create ${REPOSITORY}:latest ${REPOSITORY}:latest-amd64 ${REPOSITORY}:latest-ppc64le ${REPOSITORY}:latest-arm64v8 ${REPOSITORY}:latest-s390x
           docker manifest annotate ${REPOSITORY}:latest ${REPOSITORY}:latest-amd64 --arch amd64
           docker manifest annotate ${REPOSITORY}:latest ${REPOSITORY}:latest-ppc64le --arch ppc64le
           docker manifest annotate ${REPOSITORY}:latest ${REPOSITORY}:latest-arm64v8 --arch arm64
+          docker manifest annotate ${REPOSITORY}:latest ${REPOSITORY}:latest-s390x --arch s390x
           docker manifest push ${REPOSITORY}:latest
-          docker manifest create ${REPOSITORY}:${GITHUB_REF##*/} ${REPOSITORY}:${GITHUB_REF##*/}-amd64 ${REPOSITORY}:${GITHUB_REF##*/}-ppc64le ${REPOSITORY}:${GITHUB_REF##*/}-arm64v8
+          docker manifest create ${REPOSITORY}:${GITHUB_REF##*/} ${REPOSITORY}:${GITHUB_REF##*/}-amd64 ${REPOSITORY}:${GITHUB_REF##*/}-ppc64le ${REPOSITORY}:${GITHUB_REF##*/}-arm64v8 ${REPOSITORY}:${GITHUB_REF##*/}-s390x
           docker manifest annotate ${REPOSITORY}:${GITHUB_REF##*/} ${REPOSITORY}:${GITHUB_REF##*/}-amd64 --arch amd64
           docker manifest annotate ${REPOSITORY}:${GITHUB_REF##*/} ${REPOSITORY}:${GITHUB_REF##*/}-ppc64le --arch ppc64le
           docker manifest annotate ${REPOSITORY}:${GITHUB_REF##*/} ${REPOSITORY}:${GITHUB_REF##*/}-arm64v8 --arch arm64
+          docker manifest annotate ${REPOSITORY}:${GITHUB_REF##*/} ${REPOSITORY}:${GITHUB_REF##*/}-s390x --arch s390x
           docker manifest push ${REPOSITORY}:${GITHUB_REF##*/}
diff --git a/.github/workflows/docker-build.yml b/.github/workflows/docker-build.yml
index fcea47efc..08e5983fd 100644
--- a/.github/workflows/docker-build.yml
+++ b/.github/workflows/docker-build.yml
@@ -17,6 +17,9 @@ jobs:
   
       - name: Build latest-ppc64le
         run: docker build -t ${REPOSITORY}:latest-ppc64le -f deployments/Dockerfile.ppc64le .
+
+      - name: Build latest-s390x
+        run: docker build -t ${REPOSITORY}:latest-s390x -f deployments/Dockerfile.s390x .
   
       - name: Build latest-origin
         run: docker build -t ${REPOSITORY}:latest-origin -f deployments/Dockerfile.openshift .
diff --git a/.github/workflows/go-build-s390x.yml b/.github/workflows/go-build-s390x.yml
new file mode 100644
index 000000000..9ec559976
--- /dev/null
+++ b/.github/workflows/go-build-s390x.yml
@@ -0,0 +1,25 @@
+name: Go-build-s390x
+on: [push, pull_request]
+jobs:
+
+  build:
+    name: Build and test
+    runs-on: ubuntu-latest
+    if: >
+      (( github.event.pull_request.head.repo.owner.login != github.event.pull_request.base.repo.owner.login ) &&
+        github.event_name == 'pull_request' ) || (github.event_name == 'push' && github.event.commits != '[]' )
+    env:
+      GO111MODULE: on
+      TARGET: s390x
+    steps:
+      - name: Set up Go 1.13
+        uses: actions/setup-go@v1
+        with:
+          go-version: 1.13
+        id: go
+  
+      - name: Check out code into the Go module directory
+        uses: actions/checkout@v2
+  
+      - name: Build
+        run: GOARCH="${TARGET}" ./hack/build-go.sh
diff --git a/deployments/Dockerfile.s390x b/deployments/Dockerfile.s390x
new file mode 100644
index 000000000..af59c3b14
--- /dev/null
+++ b/deployments/Dockerfile.s390x
@@ -0,0 +1,19 @@
+# This Dockerfile is used to build the image available on DockerHub
+FROM golang:1.13 as build
+
+# Add everything
+ADD . /usr/src/multus-cni
+
+ENV GOARCH "s390x"
+ENV GOOS "linux"
+
+RUN  cd /usr/src/multus-cni && \
+     ./hack/build-go.sh
+
+# build s390x container
+FROM s390x/python:3-slim
+COPY --from=build /usr/src/multus-cni /usr/src/multus-cni
+WORKDIR /
+ADD ./images/entrypoint.sh /
+
+ENTRYPOINT ["/entrypoint.sh"]
diff --git a/images/entrypoint.sh b/images/entrypoint.sh
index 9997b7d20..0ae9d4c2c 100755
--- a/images/entrypoint.sh
+++ b/images/entrypoint.sh
@@ -77,6 +77,10 @@ function warn()
     log "WARN: {$1}"
 }
 
+if ! type python3 &> /dev/null; then
+	alias python=python3
+fi
+
 # Parse parameters given as arguments to this script.
 while [ "$1" != "" ]; do
     PARAM=`echo $1 | awk -F= '{print $1}'`
@@ -314,7 +318,7 @@ if [ "$MULTUS_CONF_FILE" == "auto" ]; then
 
       if [ "$OVERRIDE_NETWORK_NAME" == "true" ]; then
         MASTER_PLUGIN_NET_NAME="$(cat $MULTUS_AUTOCONF_DIR/$MASTER_PLUGIN | \
-            python -c 'import json,sys;print json.load(sys.stdin)["name"]')"
+            python -c 'import json,sys;print(json.load(sys.stdin)["name"])')"
       else
         MASTER_PLUGIN_NET_NAME="multus-cni-network"
       fi
diff --git a/images/multus-daemonset-crio.yml b/images/multus-daemonset-crio.yml
index 5e7d7fdd4..2adeda76b 100644
--- a/images/multus-daemonset-crio.yml
+++ b/images/multus-daemonset-crio.yml
@@ -356,3 +356,73 @@ spec:
             items:
             - key: cni-conf.json
               path: 70-multus.conf
+---
+apiVersion: apps/v1
+kind: DaemonSet
+metadata:
+  name: kube-multus-ds-s390x
+  namespace: kube-system
+  labels:
+    tier: node
+    app: multus
+    name: multus
+spec:
+  selector:
+    matchLabels:
+      name: multus
+  updateStrategy:
+    type: RollingUpdate
+  template:
+    metadata:
+      labels:
+        tier: node
+        app: multus
+        name: multus
+    spec:
+      hostNetwork: true
+      nodeSelector:
+        kubernetes.io/arch: s390x
+      tolerations:
+      - operator: Exists
+        effect: NoSchedule
+      serviceAccountName: multus
+      containers:
+      - name: kube-multus
+        # crio support requires multus:latest for now. support 3.3 or later.
+        image: docker.io/nfvpe/multus:stable-s390x
+        command: ["/entrypoint.sh"]
+        args:
+        - "--cni-version=0.3.1"
+        - "--cni-bin-dir=/host/usr/libexec/cni"
+        - "--multus-conf-file=auto"
+        - "--restart-crio=true"
+        resources:
+          requests:
+            cpu: "100m"
+            memory: "90Mi"
+          limits:
+            cpu: "100m"
+            memory: "90Mi"
+        securityContext:
+          privileged: true
+        volumeMounts:
+        - name: cni
+          mountPath: /host/etc/cni/net.d
+        - name: cnibin
+          mountPath: /host/usr/libexec/cni
+        - name: multus-cfg
+          mountPath: /tmp/multus-conf
+      terminationGracePeriodSeconds: 10
+      volumes:
+        - name: cni
+          hostPath:
+            path: /etc/cni/net.d
+        - name: cnibin
+          hostPath:
+            path: /usr/libexec/cni
+        - name: multus-cfg
+          configMap:
+            name: multus-cni-config
+            items:
+            - key: cni-conf.json
+              path: 70-multus.conf
diff --git a/images/multus-daemonset.yml b/images/multus-daemonset.yml
index ff204ea68..ce470952a 100644
--- a/images/multus-daemonset.yml
+++ b/images/multus-daemonset.yml
@@ -341,3 +341,70 @@ spec:
             items:
             - key: cni-conf.json
               path: 70-multus.conf
+---
+apiVersion: apps/v1
+kind: DaemonSet
+metadata:
+  name: kube-multus-ds-s390x
+  namespace: kube-system
+  labels:
+    tier: node
+    app: multus
+    name: multus
+spec:
+  selector:
+    matchLabels:
+      name: multus
+  updateStrategy:
+    type: RollingUpdate
+  template:
+    metadata:
+      labels:
+        tier: node
+        app: multus
+        name: multus
+    spec:
+      hostNetwork: true
+      nodeSelector:
+        kubernetes.io/arch: s390x
+      tolerations:
+      - operator: Exists
+        effect: NoSchedule
+      serviceAccountName: multus
+      containers:
+      - name: kube-multus
+        image: docker.io/nfvpe/multus:stable-s390x
+        command: ["/entrypoint.sh"]
+        args:
+        - "--multus-conf-file=auto"
+        - "--cni-version=0.3.1"
+        resources:
+          requests:
+            cpu: "100m"
+            memory: "90Mi"
+          limits:
+            cpu: "100m"
+            memory: "90Mi"
+        securityContext:
+          privileged: true
+        volumeMounts:
+        - name: cni
+          mountPath: /host/etc/cni/net.d
+        - name: cnibin
+          mountPath: /host/opt/cni/bin
+        - name: multus-cfg
+          mountPath: /tmp/multus-conf
+      terminationGracePeriodSeconds: 10
+      volumes:
+        - name: cni
+          hostPath:
+            path: /etc/cni/net.d
+        - name: cnibin
+          hostPath:
+            path: /opt/cni/bin
+        - name: multus-cfg
+          configMap:
+            name: multus-cni-config
+            items:
+            - key: cni-conf.json
+              path: 70-multus.conf