diff --git a/drivers/raw/ntb/ntb.c b/drivers/raw/ntb/ntb.c
index 46ac02e5ab..f5e773c53b 100644
--- a/drivers/raw/ntb/ntb.c
+++ b/drivers/raw/ntb/ntb.c
@@ -1398,6 +1398,10 @@ ntb_init_hw(struct rte_rawdev *dev, struct rte_pci_device *pci_dev)
 
 	/* Init doorbell. */
 	hw->db_valid_mask = RTE_LEN2MASK(hw->db_cnt, uint64_t);
+	/* Clear all valid doorbell bits before registering intr handler */
+	if (hw->ntb_ops->db_clear == NULL)
+		return -ENOTSUP;
+	(*hw->ntb_ops->db_clear)(dev, hw->db_valid_mask);
 
 	intr_handle = pci_dev->intr_handle;
 	/* Register callback func to eal lib */