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Awesome project, just started using it, with excellent results, much thanks!
I found that compiling mex files with a 64bit version of Matlab, on Windows 7 x64 required the Windows 7.1 SDK, not Visual Express 2010 (VC10 doesn't include a 64-bit compiler, so one needs the SDK to get the 64 bit compiler).
Also, as a note to anyone else struggling, I needed to use Matlab version r2011b, as I could never get r2011a to find the sdk.
Anyway, one small change to the make script allows for successful compilation:
elseif ~isempty(strfind(c.Name,'Microsoft SDK'))
s = 'vc10';
(*side note: I'm using the x64 pre-built opencv binaries)