Switch branches/tags
Nothing to show
Find file History
Fetching latest commit…
Cannot retrieve the latest commit at this time.
Permalink
..
Failed to load latest commit information.
DINTO 1.2 additional material
DINTO_1.2.owl.zip
README.txt

README.txt

Version: DINTO 1.2
Launched: June 2015

DINTO 1.2 is an extended version of DINTO 1 that includes information about adverse drug reactions (ADRs) and their relationships to pharmacological entities included in the ontology. To create this version, we have imported a reduced version of the Ontology for Adverse Events (OAE version 1.1.247), including only the top class 'adverse event' and its subclasses. In addition to this, we have imported drug-ADR relationships for the database SIDER, which can be used with SWRL rules to infer DDIs occurring by the addition of a common ADR.

In addition to this, addional material includes:
    
DINTO 1.2 subset: This file contains the subsets of the ontologies reused to be imported in DINTO.
      OAE_DINTO_subset.owl is the fragment imported from the Ontology of Adverse Events (OAE) to DINTO.

DINTO 1.2 reduced version: This file contains the reduced version of DINTO 1.2 and the SWRL rule used to infer possible ADRs.
      DINTO_1.2_IExp4.owl
Experiments using this version and rule are described in:
        Herrero-Zazo, María; Segura-Bedmar, Isabel; Hastings, Janna; Martínez, Paloma (2015). DINTO: Using OWL ontologies and SWRL rules to infer drug-drug interactions and their mechanisms. Journal of Chemical Information and Modeling. Just Accepted Manuscript. DOI: 10.1021/acs.jcim.5b00119