diff --git a/src/langsmith/troubleshooting-studio.mdx b/src/langsmith/troubleshooting-studio.mdx
index 3ee179167a..d02bfe51d3 100644
--- a/src/langsmith/troubleshooting-studio.mdx
+++ b/src/langsmith/troubleshooting-studio.mdx
@@ -36,6 +36,53 @@ Use this URL in Safari to load Studio. Here, the `baseUrl` parameter specifies y
 
 Chrome and other Chromium browsers allow HTTP on localhost. Use `langgraph dev` without additional configuration.
 
+## Chrome connection issues
+
+Starting with Chrome version 142, you may experience "Failed to initialize Studio" errors with "TypeError: Failed to fetch" when trying to connect [LangSmith Studio](/langsmith/studio) to your local development server via [`langgraph dev`](/langsmith/cli). This occurs even when the API server at `http://127.0.0.1:2024/docs` loads successfully.
+
+**Root Cause:** Chrome 142 fully enforces the Private Network Access (PNA) specification with no fallback, which blocks HTTPS sites (like `https://smith.langchain.com`) from accessing HTTP localhost servers by default.
+
+### Symptoms
+
+- Running `langgraph dev` starts the server successfully.
+- Navigating to `http://127.0.0.1:2024/docs` shows the API documentation correctly.
+- LangSmith Studio at `https://smith.langchain.com` shows: "Failed to initialize Studio - Please verify if the API server is running or accessible from the browser. TypeError: Failed to fetch".
+- Browser console shows errors like: `Permission was denied for this request to access the 'unknown' address space`.
+
+### Solution: Allow local network access in Chrome
+
+1. Open LangSmith Studio at `https://smith.langchain.com` in Chrome.
+2. Click the **lock icon** (or site information icon) to the left of the address bar.
+3. Look for the **"Local network access"** option in the dropdown.
+4. Change the setting from **"Ask (default)"** or **"Block"** to **"Allow"**.
+5. Reload the page.
+
+Studio should now connect to your local development server successfully.
+
+### Additional troubleshooting
+
+**Check for browser extension conflicts**
+
+Browser extensions (especially Ollama Chrome extension or AI model extensions) can interfere with localhost connections:
+
+1. Disable all browser extensions temporarily.
+2. Restart Chrome.
+3. Try connecting to Studio again.
+4. If it works, re-enable extensions one by one to identify the culprit.
+
+**Verify dependencies are up to date**
+
+```shell
+pip install -U "langgraph-cli[inmem]"
+```
+
+**Clear browser cache and site data**
+
+1. In Chrome, go to **Settings** > **Privacy and Security** > **Site Settings**.
+2. Find `https://smith.langchain.com` in the list.
+3. Click **Clear data**.
+4. Restart Chrome and try again.
+
 ## Brave Connection Issues
 
 Brave blocks plain-HTTP traffic on localhost when Brave Shields are enabled. When running Studio with `langgraph dev`, you may see "Failed to load assistants" errors.