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Integrating external controls into association test
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DESCRIPTION
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README.md

README.md

iECAT R-package

iECAT is an R-package for a method to integrating external controls in rare variant tests. It has functions for gene-based tests, including SKAT, and SKAT-O, and single variant test.

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Reference

  • Lee, S., Kim, S., Fuchsberger, C. (2017) Improving power for rare variant tests by integrating external controls, Genetic Epidemiology, in press, (preprint: Biorxiv, https://doi.org/10.1101/081711)
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