Interactive tool for assessing confounding of DE results with RNA degradation

[lcolladotor]

We will build an interactive website, likely powered by shiny, such that users can upload their differential expression results at the gene-level and make DEqual plots to assess if their results appear to be confounded by RNA degradation.

This tool (website) will enable users to check publicly available differential expression results and identify genes which could potentially be false positives. The website will generate an automated report that can then be shared with collaborators. The function for making this report will also be available as an R function that can be used in an non-interactive way.

If possible (due to memory constraints), this tool will also support exon-level, transcript-level, and/or exon-exon junction level DE results.