diff --git a/llvm/test/CodeGen/X86/vector-shuffle-256-v32.ll b/llvm/test/CodeGen/X86/vector-shuffle-256-v32.ll
index 58401a2e34283..1e7745a4b8836 100644
--- a/llvm/test/CodeGen/X86/vector-shuffle-256-v32.ll
+++ b/llvm/test/CodeGen/X86/vector-shuffle-256-v32.ll
@@ -5109,6 +5109,63 @@ define <32 x i8> @PR55066(<32 x i8> %a0) {
   ret <32 x i8> %shuffle
 }
 
+define <4 x i64> @PR66150(ptr %b) {
+; AVX1-LABEL: PR66150:
+; AVX1:       # %bb.0:
+; AVX1-NEXT:    vmovd {{.*#+}} xmm0 = mem[0],zero,zero,zero
+; AVX1-NEXT:    vpunpcklbw {{.*#+}} xmm0 = xmm0[0,0,1,1,2,2,3,3,4,4,5,5,6,6,7,7]
+; AVX1-NEXT:    vpshuflw {{.*#+}} xmm1 = xmm0[0,0,1,1,4,5,6,7]
+; AVX1-NEXT:    vpshuflw {{.*#+}} xmm0 = xmm0[2,2,3,3,4,5,6,7]
+; AVX1-NEXT:    vinsertf128 $1, %xmm0, %ymm1, %ymm0
+; AVX1-NEXT:    vshufps {{.*#+}} ymm0 = ymm0[0,0,1,1,4,4,5,5]
+; AVX1-NEXT:    retq
+;
+; AVX2-LABEL: PR66150:
+; AVX2:       # %bb.0:
+; AVX2-NEXT:    vmovd {{.*#+}} xmm0 = mem[0],zero,zero,zero
+; AVX2-NEXT:    vpermq {{.*#+}} ymm0 = ymm0[0,1,0,1]
+; AVX2-NEXT:    vpshufb {{.*#+}} ymm0 = ymm0[0,0,0,0,0,0,0,0,1,1,1,1,1,1,1,1,18,18,18,18,18,18,18,18,19,19,19,19,19,19,19,19]
+; AVX2-NEXT:    retq
+;
+; AVX512VLBW-LABEL: PR66150:
+; AVX512VLBW:       # %bb.0:
+; AVX512VLBW-NEXT:    vmovd {{.*#+}} xmm0 = mem[0],zero,zero,zero
+; AVX512VLBW-NEXT:    vpermq {{.*#+}} ymm0 = ymm0[0,1,0,1]
+; AVX512VLBW-NEXT:    vpshufb {{.*#+}} ymm0 = ymm0[0,0,0,0,0,0,0,0,1,1,1,1,1,1,1,1,18,18,18,18,18,18,18,18,19,19,19,19,19,19,19,19]
+; AVX512VLBW-NEXT:    retq
+;
+; AVX512VLVBMI-LABEL: PR66150:
+; AVX512VLVBMI:       # %bb.0:
+; AVX512VLVBMI-NEXT:    vmovd {{.*#+}} xmm0 = mem[0],zero,zero,zero
+; AVX512VLVBMI-NEXT:    vmovdqa {{.*#+}} ymm1 = [0,0,0,0,0,0,0,0,1,1,1,1,1,1,1,1,2,2,2,2,2,2,2,2,3,3,3,3,3,3,3,3]
+; AVX512VLVBMI-NEXT:    vpermb %ymm0, %ymm1, %ymm0
+; AVX512VLVBMI-NEXT:    retq
+;
+; XOPAVX1-LABEL: PR66150:
+; XOPAVX1:       # %bb.0:
+; XOPAVX1-NEXT:    vmovd {{.*#+}} xmm0 = mem[0],zero,zero,zero
+; XOPAVX1-NEXT:    vpunpcklbw {{.*#+}} xmm0 = xmm0[0,0,1,1,2,2,3,3,4,4,5,5,6,6,7,7]
+; XOPAVX1-NEXT:    vpshuflw {{.*#+}} xmm1 = xmm0[0,0,1,1,4,5,6,7]
+; XOPAVX1-NEXT:    vpshuflw {{.*#+}} xmm0 = xmm0[2,2,3,3,4,5,6,7]
+; XOPAVX1-NEXT:    vinsertf128 $1, %xmm0, %ymm1, %ymm0
+; XOPAVX1-NEXT:    vshufps {{.*#+}} ymm0 = ymm0[0,0,1,1,4,4,5,5]
+; XOPAVX1-NEXT:    retq
+;
+; XOPAVX2-LABEL: PR66150:
+; XOPAVX2:       # %bb.0:
+; XOPAVX2-NEXT:    vmovd {{.*#+}} xmm0 = mem[0],zero,zero,zero
+; XOPAVX2-NEXT:    vpermq {{.*#+}} ymm0 = ymm0[0,1,0,1]
+; XOPAVX2-NEXT:    vpshufb {{.*#+}} ymm0 = ymm0[0,0,0,0,0,0,0,0,1,1,1,1,1,1,1,1,18,18,18,18,18,18,18,18,19,19,19,19,19,19,19,19]
+; XOPAVX2-NEXT:    retq
+  %tmp1 = load i32, ptr %b, align 4
+  %tmp2 = insertelement <8 x i32> undef, i32 %tmp1, i64 0
+  %tmp3 = shufflevector <8 x i32> %tmp2, <8 x i32> poison, <8 x i32> <i32 0, i32 poison, i32 poison, i32 poison, i32 0, i32 poison, i32 poison, i32 poison>
+  %tmp4 = bitcast <8 x i32> %tmp3 to <32 x i8>
+  %tmp5 = shufflevector <32 x i8> %tmp4, <32 x i8> poison, <32 x i32> <i32 0, i32 0, i32 0, i32 0, i32 0, i32 0, i32 0, i32 0, i32 1, i32 1, i32 1, i32 1, i32 1, i32 1, i32 1, i32 1, i32 18, i32 18, i32 18, i32 18, i32 18, i32 18, i32 18, i32 18, i32 19, i32 19, i32 19, i32 19, i32 19, i32 19, i32 19, i32 19>
+  %tmp6 = bitcast <32 x i8> %tmp5 to <4 x i64>
+  ret <4 x i64> %tmp6
+}
+
 define <32 x i8> @insert_dup_mem_v32i8_i32(ptr %ptr) {
 ; AVX1-LABEL: insert_dup_mem_v32i8_i32:
 ; AVX1:       # %bb.0: