diff --git a/compiler-rt/test/cfi/lit.cfg.py b/compiler-rt/test/cfi/lit.cfg.py
index cbffe6ea8a65a8..2f2d1ddcaa7920 100644
--- a/compiler-rt/test/cfi/lit.cfg.py
+++ b/compiler-rt/test/cfi/lit.cfg.py
@@ -13,7 +13,11 @@ def build_invocation(compile_flags):
 
 config.substitutions.append((r"%clang ", clang + ' '))
 config.substitutions.append((r"%clangxx ", clangxx + ' '))
-if config.lto_supported:
+
+if 'darwin' in config.available_features:
+  # -fsanitize=cfi is not supported on Darwin hosts
+  config.unsupported = True
+elif config.lto_supported:
   clang_cfi = clang + '-fsanitize=cfi '
 
   if config.cfi_lit_test_mode == "Devirt":