diff --git a/clang/docs/ReleaseNotes.rst b/clang/docs/ReleaseNotes.rst
index 1e77386aede2e..cdef43f2011bc 100644
--- a/clang/docs/ReleaseNotes.rst
+++ b/clang/docs/ReleaseNotes.rst
@@ -570,6 +570,7 @@ X86 Support
 - Support ISA of ``USER_MSR``.
   * Support intrinsic of ``_urdmsr``.
   * Support intrinsic of ``_uwrmsr``.
+- Support ISA of ``AVX10.1``.
 
 Arm and AArch64 Support
 ^^^^^^^^^^^^^^^^^^^^^^^
diff --git a/clang/include/clang/Driver/Options.td b/clang/include/clang/Driver/Options.td
index 640044622fc09..95849fef787ed 100644
--- a/clang/include/clang/Driver/Options.td
+++ b/clang/include/clang/Driver/Options.td
@@ -197,6 +197,9 @@ def m_wasm_Features_Driver_Group : OptionGroup<"<wasm driver features group>">,
 def m_x86_Features_Group : OptionGroup<"<x86 features group>">,
                            Group<m_Group>, Visibility<[ClangOption, CLOption]>,
                            DocName<"X86">;
+def m_x86_AVX10_Features_Group : OptionGroup<"<x86 AVX10 features group>">,
+                                 Group<m_Group>, Visibility<[ClangOption, CLOption]>,
+                                 DocName<"X86 AVX10">;
 def m_riscv_Features_Group : OptionGroup<"<riscv features group>">,
                              Group<m_Group>, DocName<"RISC-V">;
 def m_ve_Features_Group : OptionGroup<"<ve features group>">,
@@ -5754,6 +5757,12 @@ def msse4a : Flag<["-"], "msse4a">, Group<m_x86_Features_Group>;
 def mno_sse4a : Flag<["-"], "mno-sse4a">, Group<m_x86_Features_Group>;
 def mavx : Flag<["-"], "mavx">, Group<m_x86_Features_Group>;
 def mno_avx : Flag<["-"], "mno-avx">, Group<m_x86_Features_Group>;
+def mavx10_1_256 : Flag<["-"], "mavx10.1-256">, Group<m_x86_AVX10_Features_Group>;
+def mno_avx10_1_256 : Flag<["-"], "mno-avx10.1-256">, Group<m_x86_AVX10_Features_Group>;
+def mavx10_1_512 : Flag<["-"], "mavx10.1-512">, Group<m_x86_AVX10_Features_Group>;
+def mno_avx10_1_512 : Flag<["-"], "mno-avx10.1-512">, Group<m_x86_AVX10_Features_Group>;
+def mavx10_1 : Flag<["-"], "mavx10.1">, Alias<mavx10_1_256>;
+def mno_avx10_1 : Flag<["-"], "mno-avx10.1">, Alias<mno_avx10_1_256>;
 def mavx2 : Flag<["-"], "mavx2">, Group<m_x86_Features_Group>;
 def mno_avx2 : Flag<["-"], "mno-avx2">, Group<m_x86_Features_Group>;
 def mavx512f : Flag<["-"], "mavx512f">, Group<m_x86_Features_Group>;
diff --git a/clang/lib/Basic/Targets/X86.cpp b/clang/lib/Basic/Targets/X86.cpp
index bea5c52a7b8d7..ec9a518e56449 100644
--- a/clang/lib/Basic/Targets/X86.cpp
+++ b/clang/lib/Basic/Targets/X86.cpp
@@ -121,6 +121,7 @@ bool X86TargetInfo::initFeatureMap(
   std::vector<std::string> UpdatedFeaturesVec;
   bool HasEVEX512 = true;
   bool HasAVX512F = false;
+  bool HasAVX10 = false;
   for (const auto &Feature : FeaturesVec) {
     // Expand general-regs-only to -x86, -mmx and -sse
     if (Feature == "+general-regs-only") {
@@ -130,17 +131,35 @@ bool X86TargetInfo::initFeatureMap(
       continue;
     }
 
-    if (!HasAVX512F && Feature.substr(0, 7) == "+avx512")
+    if (Feature.substr(0, 7) == "+avx10.") {
+      HasAVX10 = true;
       HasAVX512F = true;
-    if (HasAVX512F && Feature == "-avx512f")
+      if (Feature.substr(Feature.size() - 3, 3) == "512") {
+        HasEVEX512 = true;
+      } else if (Feature.substr(7, 2) == "1-") {
+        HasEVEX512 = false;
+      }
+    } else if (!HasAVX512F && Feature.substr(0, 7) == "+avx512") {
+      HasAVX512F = true;
+    } else if (HasAVX512F && Feature == "-avx512f") {
+      HasAVX512F = false;
+    } else if (HasAVX10 && Feature == "-avx10.1-256") {
+      HasAVX10 = false;
       HasAVX512F = false;
-    if (HasEVEX512 && Feature == "-evex512")
+    } else if (!HasEVEX512 && Feature == "+evex512") {
+      HasEVEX512 = true;
+    } else if (HasEVEX512 && Feature == "-avx10.1-512") {
       HasEVEX512 = false;
+    } else if (HasEVEX512 && Feature == "-evex512") {
+      HasEVEX512 = false;
+    }
 
     UpdatedFeaturesVec.push_back(Feature);
   }
   if (HasAVX512F && HasEVEX512)
     UpdatedFeaturesVec.push_back("+evex512");
+  else if (HasAVX10)
+    UpdatedFeaturesVec.push_back("-evex512");
 
   if (!TargetInfo::initFeatureMap(Features, Diags, CPU, UpdatedFeaturesVec))
     return false;
@@ -241,6 +260,10 @@ bool X86TargetInfo::handleTargetFeatures(std::vector<std::string> &Features,
       HasGFNI = true;
     } else if (Feature == "+evex512") {
       HasEVEX512 = true;
+    } else if (Feature == "+avx10.1-256") {
+      HasAVX10_1 = true;
+    } else if (Feature == "+avx10.1-512") {
+      HasAVX10_1_512 = true;
     } else if (Feature == "+avx512cd") {
       HasAVX512CD = true;
     } else if (Feature == "+avx512vpopcntdq") {
@@ -748,6 +771,10 @@ void X86TargetInfo::getTargetDefines(const LangOptions &Opts,
 
   if (HasEVEX512)
     Builder.defineMacro("__EVEX512__");
+  if (HasAVX10_1)
+    Builder.defineMacro("__AVX10_1__");
+  if (HasAVX10_1_512)
+    Builder.defineMacro("__AVX10_1_512__");
   if (HasAVX512CD)
     Builder.defineMacro("__AVX512CD__");
   if (HasAVX512VPOPCNTDQ)
@@ -973,6 +1000,8 @@ bool X86TargetInfo::isValidFeatureName(StringRef Name) const {
       .Case("amx-int8", true)
       .Case("amx-tile", true)
       .Case("avx", true)
+      .Case("avx10.1-256", true)
+      .Case("avx10.1-512", true)
       .Case("avx2", true)
       .Case("avx512f", true)
       .Case("avx512cd", true)
@@ -1081,6 +1110,8 @@ bool X86TargetInfo::hasFeature(StringRef Feature) const {
       .Case("amx-int8", HasAMXINT8)
       .Case("amx-tile", HasAMXTILE)
       .Case("avx", SSELevel >= AVX)
+      .Case("avx10.1-256", HasAVX10_1)
+      .Case("avx10.1-512", HasAVX10_1_512)
       .Case("avx2", SSELevel >= AVX2)
       .Case("avx512f", SSELevel >= AVX512F)
       .Case("avx512cd", HasAVX512CD)
diff --git a/clang/lib/Basic/Targets/X86.h b/clang/lib/Basic/Targets/X86.h
index 298db55c67442..99a64501d263c 100644
--- a/clang/lib/Basic/Targets/X86.h
+++ b/clang/lib/Basic/Targets/X86.h
@@ -95,6 +95,8 @@ class LLVM_LIBRARY_VISIBILITY X86TargetInfo : public TargetInfo {
   bool HasLWP = false;
   bool HasFMA = false;
   bool HasF16C = false;
+  bool HasAVX10_1 = false;
+  bool HasAVX10_1_512 = false;
   bool HasEVEX512 = false;
   bool HasAVX512CD = false;
   bool HasAVX512VPOPCNTDQ = false;
diff --git a/clang/lib/Driver/ToolChains/Arch/X86.cpp b/clang/lib/Driver/ToolChains/Arch/X86.cpp
index cf2bc63d74ada..848c26ddb43e4 100644
--- a/clang/lib/Driver/ToolChains/Arch/X86.cpp
+++ b/clang/lib/Driver/ToolChains/Arch/X86.cpp
@@ -229,6 +229,31 @@ void x86::getX86TargetFeatures(const Driver &D, const llvm::Triple &Triple,
         << D.getOpts().getOptionName(LVIOpt);
   }
 
+  bool HasAVX10 = false;
+  for (const Arg *A : Args.filtered(options::OPT_m_x86_AVX10_Features_Group)) {
+    StringRef Name = A->getOption().getName();
+    A->claim();
+
+    // Skip over "-m".
+    assert(Name.startswith("m") && "Invalid feature name.");
+    Name = Name.substr(1);
+
+    bool IsNegative = Name.startswith("no-");
+    if (IsNegative)
+      Name = Name.substr(3);
+
+#ifndef NDEBUG
+    assert(Name.startswith("avx10.") && "Invalid AVX10 feature name.");
+    StringRef Version, Width;
+    std::tie(Version, Width) = Name.substr(6).split('-');
+    assert(Version == "1" && "Invalid AVX10 feature name.");
+    assert((Width == "256" || Width == "512") && "Invalid AVX10 feature name.");
+#endif
+
+    Features.push_back(Args.MakeArgString((IsNegative ? "-" : "+") + Name));
+    HasAVX10 = true;
+  }
+
   // Now add any that the user explicitly requested on the command line,
   // which may override the defaults.
   for (const Arg *A : Args.filtered(options::OPT_m_x86_Features_Group,
@@ -246,9 +271,14 @@ void x86::getX86TargetFeatures(const Driver &D, const llvm::Triple &Triple,
       continue;
     }
 
+    StringRef AVX512Name = Name;
     bool IsNegative = Name.startswith("no-");
     if (IsNegative)
       Name = Name.substr(3);
+    if (HasAVX10 && (Name.startswith("avx512") || Name == "evex512")) {
+      D.Diag(diag::warn_drv_unused_argument) << AVX512Name;
+      continue;
+    }
     Features.push_back(Args.MakeArgString((IsNegative ? "-" : "+") + Name));
   }
 
diff --git a/clang/test/CodeGen/X86/avx512-error.c b/clang/test/CodeGen/X86/avx512-error.c
index 8e42105ec1127..133e7d01ea33c 100644
--- a/clang/test/CodeGen/X86/avx512-error.c
+++ b/clang/test/CodeGen/X86/avx512-error.c
@@ -1,9 +1,17 @@
-// RUN: %clang_cc1 %s -ffreestanding -triple=x86_64-unknown-unknown -target-feature +avx512bw -target-feature -evex512 -emit-llvm -o /dev/null -verify -DFEATURE_TEST=1
-// RUN: %clang_cc1 %s -ffreestanding -triple=x86_64-unknown-unknown -target-feature +avx512bw -target-feature -evex512 -emit-llvm -o /dev/null -verify -DFEATURE_TEST=2
+// RUN: %clang_cc1 %s -ffreestanding -triple=x86_64-unknown-unknown -target-feature +avx512bw -target-feature -evex512 -emit-llvm -o /dev/null -verify=noevex -DFEATURE_TEST=1
+// RUN: %clang_cc1 %s -ffreestanding -triple=x86_64-unknown-unknown -target-feature +avx512bw -target-feature -evex512 -emit-llvm -o /dev/null -verify=noevex -DFEATURE_TEST=2
+// RUN: %clang_cc1 %s -ffreestanding -triple=x86_64-unknown-unknown -target-feature +avx512bw -emit-llvm -o /dev/null -verify -DFEATURE_TEST=3
+// RUN: %clang_cc1 %s -ffreestanding -triple=x86_64-unknown-unknown -target-feature +avx10.1-256 -emit-llvm -o /dev/null -verify=noevex -DFEATURE_TEST=1
+// RUN: %clang_cc1 %s -ffreestanding -triple=x86_64-unknown-unknown -target-feature +avx10.1-256 -emit-llvm -o /dev/null -verify=noevex -DFEATURE_TEST=2
+// RUN: %clang_cc1 %s -ffreestanding -triple=x86_64-unknown-unknown -target-feature +avx10.1-512 -emit-llvm -o /dev/null -verify -DFEATURE_TEST=3
 
 #include <immintrin.h>
 
-#if FEATURE_TEST == 1
+#if FEATURE_TEST & 3
+// expected-no-diagnostics
+#endif
+
+#if FEATURE_TEST & 1
 __attribute__((target("avx512bw,evex512")))
 __m512d zmm_verify_ok(__m512d a) {
   // No error emitted if we have "evex512" feature.
@@ -12,11 +20,11 @@ __m512d zmm_verify_ok(__m512d a) {
 
 __m512d zmm_error(__m512d a) {
   // CHECK-LABEL: @test_mm512_sqrt_pd
-  return __builtin_ia32_sqrtpd512(a, _MM_FROUND_CUR_DIRECTION); // expected-error {{'__builtin_ia32_sqrtpd512' needs target feature avx512f,evex512}}
+  return __builtin_ia32_sqrtpd512(a, _MM_FROUND_CUR_DIRECTION); // noevex-error {{'__builtin_ia32_sqrtpd512' needs target feature avx512f,evex512}}
 }
 #endif
 
-#if FEATURE_TEST == 2
+#if FEATURE_TEST & 2
 __attribute__((target("avx512bw,evex512")))
 __mmask64 k64_verify_ok(__mmask64 a) {
   // No error emitted if we have "evex512" feature.
@@ -24,6 +32,6 @@ __mmask64 k64_verify_ok(__mmask64 a) {
 }
 
 __mmask64 test_knot_mask64(__mmask64 a) {
-  return _knot_mask64(a); // expected-error {{always_inline function '_knot_mask64' requires target feature 'evex512', but would be inlined into function 'test_knot_mask64' that is compiled without support for 'evex512'}}
+  return _knot_mask64(a); // noevex-error {{always_inline function '_knot_mask64' requires target feature 'evex512', but would be inlined into function 'test_knot_mask64' that is compiled without support for 'evex512'}}
 }
 #endif
diff --git a/clang/test/CodeGen/attr-target-x86.c b/clang/test/CodeGen/attr-target-x86.c
index d261c007a0a2a..304398678216f 100644
--- a/clang/test/CodeGen/attr-target-x86.c
+++ b/clang/test/CodeGen/attr-target-x86.c
@@ -36,6 +36,9 @@ void __attribute__((target("arch=x86-64-v2"))) x86_64_v2(void) {}
 void __attribute__((target("arch=x86-64-v3"))) x86_64_v3(void) {}
 void __attribute__((target("arch=x86-64-v4"))) x86_64_v4(void) {}
 
+void __attribute__((target("avx10.1-256"))) avx10_1_256(void) {}
+void __attribute__((target("avx10.1-512"))) avx10_1_512(void) {}
+
 // Check that we emit the additional subtarget and cpu features for foo and not for baz or bar.
 // CHECK: baz{{.*}} #0
 // CHECK: foo{{.*}} #1
@@ -51,13 +54,15 @@ void __attribute__((target("arch=x86-64-v4"))) x86_64_v4(void) {}
 // CHECK: lake{{.*}} #7
 // CHECK: use_before_def{{.*}} #7
 // CHECK: walrus{{.*}} #8
+// CHECK: avx10_1_256{{.*}} #12
+// CHECK: avx10_1_512{{.*}} #13
 // CHECK: #0 = {{.*}}"target-cpu"="i686" "target-features"="+cmov,+cx8,+x87" "tune-cpu"="i686"
 // CHECK: #1 = {{.*}}"target-cpu"="ivybridge" "target-features"="+avx,+cmov,+crc32,+cx16,+cx8,+f16c,+fsgsbase,+fxsr,+mmx,+pclmul,+popcnt,+rdrnd,+sahf,+sse,+sse2,+sse3,+sse4.1,+sse4.2,+ssse3,+x87,+xsave,+xsaveopt"
 // CHECK-NOT: tune-cpu
-// CHECK: #2 = {{.*}}"target-cpu"="i686" "target-features"="+cmov,+cx8,+x87,-aes,-avx,-avx2,-avx512bf16,-avx512bitalg,-avx512bw,-avx512cd,-avx512dq,-avx512er,-avx512f,-avx512fp16,-avx512ifma,-avx512pf,-avx512vbmi,-avx512vbmi2,-avx512vl,-avx512vnni,-avx512vp2intersect,-avx512vpopcntdq,-avxifma,-avxneconvert,-avxvnni,-avxvnniint16,-avxvnniint8,-f16c,-fma,-fma4,-gfni,-kl,-pclmul,-sha,-sha512,-sm3,-sm4,-sse2,-sse3,-sse4.1,-sse4.2,-sse4a,-ssse3,-vaes,-vpclmulqdq,-widekl,-xop" "tune-cpu"="i686"
+// CHECK: #2 = {{.*}}"target-cpu"="i686" "target-features"="+cmov,+cx8,+x87,-aes,-avx,-avx10.1-256,-avx10.1-512,-avx2,-avx512bf16,-avx512bitalg,-avx512bw,-avx512cd,-avx512dq,-avx512er,-avx512f,-avx512fp16,-avx512ifma,-avx512pf,-avx512vbmi,-avx512vbmi2,-avx512vl,-avx512vnni,-avx512vp2intersect,-avx512vpopcntdq,-avxifma,-avxneconvert,-avxvnni,-avxvnniint16,-avxvnniint8,-f16c,-fma,-fma4,-gfni,-kl,-pclmul,-sha,-sha512,-sm3,-sm4,-sse2,-sse3,-sse4.1,-sse4.2,-sse4a,-ssse3,-vaes,-vpclmulqdq,-widekl,-xop" "tune-cpu"="i686"
 // CHECK: #3 = {{.*}}"target-cpu"="i686" "target-features"="+cmov,+crc32,+cx8,+mmx,+popcnt,+sse,+sse2,+sse3,+sse4.1,+sse4.2,+ssse3,+x87" "tune-cpu"="i686"
-// CHECK: #4 = {{.*}}"target-cpu"="i686" "target-features"="+cmov,+cx8,+x87,-avx,-avx2,-avx512bf16,-avx512bitalg,-avx512bw,-avx512cd,-avx512dq,-avx512er,-avx512f,-avx512fp16,-avx512ifma,-avx512pf,-avx512vbmi,-avx512vbmi2,-avx512vl,-avx512vnni,-avx512vp2intersect,-avx512vpopcntdq,-avxifma,-avxneconvert,-avxvnni,-avxvnniint16,-avxvnniint8,-f16c,-fma,-fma4,-sha512,-sm3,-sm4,-sse4.1,-sse4.2,-vaes,-vpclmulqdq,-xop" "tune-cpu"="i686"
-// CHECK: #5 = {{.*}}"target-cpu"="ivybridge" "target-features"="+avx,+cmov,+crc32,+cx16,+cx8,+f16c,+fsgsbase,+fxsr,+mmx,+pclmul,+popcnt,+rdrnd,+sahf,+sse,+sse2,+sse3,+sse4.1,+sse4.2,+ssse3,+x87,+xsave,+xsaveopt,-aes,-vaes"
+// CHECK: #4 = {{.*}}"target-cpu"="i686" "target-features"="+cmov,+cx8,+x87,-avx,-avx10.1-256,-avx10.1-512,-avx2,-avx512bf16,-avx512bitalg,-avx512bw,-avx512cd,-avx512dq,-avx512er,-avx512f,-avx512fp16,-avx512ifma,-avx512pf,-avx512vbmi,-avx512vbmi2,-avx512vl,-avx512vnni,-avx512vp2intersect,-avx512vpopcntdq,-avxifma,-avxneconvert,-avxvnni,-avxvnniint16,-avxvnniint8,-f16c,-fma,-fma4,-sha512,-sm3,-sm4,-sse4.1,-sse4.2,-vaes,-vpclmulqdq,-xop" "tune-cpu"="i686"
+// CHECK: #5 = {{.*}}"target-cpu"="ivybridge" "target-features"="+avx,+cmov,+crc32,+cx16,+cx8,+f16c,+fsgsbase,+fxsr,+mmx,+pclmul,+popcnt,+rdrnd,+sahf,+sse,+sse2,+sse3,+sse4.1,+sse4.2,+ssse3,+x87,+xsave,+xsaveopt,-aes,-avx10.1-256,-avx10.1-512,-vaes"
 // CHECK-NOT: tune-cpu
 // CHECK: #6 = {{.*}}"target-cpu"="i686" "target-features"="+cmov,+cx8,+x87,-3dnow,-3dnowa,-mmx"
 // CHECK: #7 = {{.*}}"target-cpu"="lakemont" "target-features"="+cx8,+mmx"
@@ -70,3 +75,6 @@ void __attribute__((target("arch=x86-64-v4"))) x86_64_v4(void) {}
 // CHECK-SAME: "target-features"="+avx,+avx2,+bmi,+bmi2,+cmov,+crc32,+cx16,+cx8,+f16c,+fma,+fxsr,+lzcnt,+mmx,+movbe,+popcnt,+sahf,+sse,+sse2,+sse3,+sse4.1,+sse4.2,+ssse3,+x87,+xsave"
 // CHECK: "target-cpu"="x86-64-v4"
 // CHECK-SAME: "target-features"="+avx,+avx2,+avx512bw,+avx512cd,+avx512dq,+avx512f,+avx512vl,+bmi,+bmi2,+cmov,+crc32,+cx16,+cx8,+evex512,+f16c,+fma,+fxsr,+lzcnt,+mmx,+movbe,+popcnt,+sahf,+sse,+sse2,+sse3,+sse4.1,+sse4.2,+ssse3,+x87,+xsave"
+
+// CHECK: #12 = {{.*}}"target-cpu"="i686" "target-features"="+aes,+avx,+avx10.1-256,+avx2,+avx512bf16,+avx512bitalg,+avx512bw,+avx512cd,+avx512dq,+avx512f,+avx512fp16,+avx512ifma,+avx512vbmi,+avx512vbmi2,+avx512vl,+avx512vnni,+avx512vpopcntdq,+cmov,+crc32,+cx8,+f16c,+fma,+mmx,+pclmul,+popcnt,+sse,+sse2,+sse3,+sse4.1,+sse4.2,+ssse3,+vaes,+vpclmulqdq,+x87,+xsave,-avx10.1-512,-evex512"
+// CHECK: #13 = {{.*}}"target-cpu"="i686" "target-features"="+aes,+avx,+avx10.1-256,+avx10.1-512,+avx2,+avx512bf16,+avx512bitalg,+avx512bw,+avx512cd,+avx512dq,+avx512f,+avx512fp16,+avx512ifma,+avx512vbmi,+avx512vbmi2,+avx512vl,+avx512vnni,+avx512vpopcntdq,+cmov,+crc32,+cx8,+evex512,+f16c,+fma,+mmx,+pclmul,+popcnt,+sse,+sse2,+sse3,+sse4.1,+sse4.2,+ssse3,+vaes,+vpclmulqdq,+x87,+xsave"
diff --git a/clang/test/CodeGen/target-avx-abi-diag.c b/clang/test/CodeGen/target-avx-abi-diag.c
index 34995dc471545..72de0fa2a39bd 100644
--- a/clang/test/CodeGen/target-avx-abi-diag.c
+++ b/clang/test/CodeGen/target-avx-abi-diag.c
@@ -5,6 +5,10 @@
 // RUN: %clang_cc1 %s -triple=x86_64-linux-gnu -target-feature +avx512f -target-feature -evex512 -verify=avx512-256 -DAVX512_ERR=1 -o - -S
 // RUN: %clang_cc1 %s -triple=x86_64-linux-gnu -target-feature +avx512f -target-feature -evex512 -verify=avx512-256 -DAVX512_ERR=2 -o - -S
 // RUN: %clang_cc1 %s -triple=x86_64-linux-gnu -target-feature +avx512f -target-feature -evex512 -verify=avx512-256 -DAVX512_ERR=3 -o - -S
+// RUN: %clang_cc1 %s -triple=x86_64-linux-gnu -target-feature +avx10.1-512 -verify=both -o - -S
+// RUN: %clang_cc1 %s -triple=x86_64-linux-gnu -target-feature +avx10.1-256 -verify=avx512-256 -DAVX512_ERR=1 -o - -S
+// RUN: %clang_cc1 %s -triple=x86_64-linux-gnu -target-feature +avx10.1-256 -verify=avx512-256 -DAVX512_ERR=2 -o - -S
+// RUN: %clang_cc1 %s -triple=x86_64-linux-gnu -target-feature +avx10.1-256 -verify=avx512-256 -DAVX512_ERR=3 -o - -S
 // REQUIRES: x86-registered-target
 
 // both-no-diagnostics
diff --git a/clang/test/Driver/x86-target-features.c b/clang/test/Driver/x86-target-features.c
index 464dcda504bbd..3ef11ffcb695d 100644
--- a/clang/test/Driver/x86-target-features.c
+++ b/clang/test/Driver/x86-target-features.c
@@ -374,6 +374,26 @@
 // EVEX512: "-target-feature" "+evex512"
 // NO-EVEX512: "-target-feature" "-evex512"
 
+// RUN: %clang --target=i386 -mavx10.1 %s -### -o %t.o 2>&1 | FileCheck -check-prefix=AVX10_1_256 %s
+// RUN: %clang --target=i386 -mavx10.1-256 %s -### -o %t.o 2>&1 | FileCheck -check-prefix=AVX10_1_256 %s
+// RUN: %clang --target=i386 -mavx10.1-512 %s -### -o %t.o 2>&1 | FileCheck -check-prefix=AVX10_1_512 %s
+// RUN: %clang --target=i386 -mavx10.1-256 -mavx10.1-512 %s -### -o %t.o 2>&1 | FileCheck -check-prefix=AVX10_1_512 %s
+// RUN: %clang --target=i386 -mavx10.1-512 -mavx10.1-256 %s -### -o %t.o 2>&1 | FileCheck -check-prefix=AVX10_1_256 %s
+// RUN: not %clang --target=i386 -march=i386 -mavx10.1-128 %s -### -o %t.o 2>&1 | FileCheck -check-prefix=BAD-AVX10 %s
+// RUN: not %clang --target=i386 -march=i386 -mavx10.a-256 %s -### -o %t.o 2>&1 | FileCheck -check-prefix=BAD-AVX10 %s
+// RUN: not %clang --target=i386 -march=i386 -mavx10.1024-512 %s -### -o %t.o 2>&1 | FileCheck -check-prefix=BAD-AVX10 %s
+// RUN: %clang --target=i386 -march=i386 -mavx10.1 -mavx512f %s -### -o %t.o 2>&1 | FileCheck -check-prefix=AVX10-AVX512 %s
+// RUN: %clang --target=i386 -march=i386 -mavx10.1 -mno-avx512f %s -### -o %t.o 2>&1 | FileCheck -check-prefix=AVX10-AVX512 %s
+// RUN: %clang --target=i386 -march=i386 -mavx10.1 -mevex512 %s -### -o %t.o 2>&1 | FileCheck -check-prefix=AVX10-EVEX512 %s
+// RUN: %clang --target=i386 -march=i386 -mavx10.1 -mno-evex512 %s -### -o %t.o 2>&1 | FileCheck -check-prefix=AVX10-EVEX512 %s
+// AVX10_1_256: "-target-feature" "+avx10.1-256"
+// AVX10_1_512: "-target-feature" "+avx10.1-512"
+// BAD-AVX10: error: unknown argument{{:?}} '-mavx10.{{.*}}'
+// AVX10-AVX512: warning: argument unused during compilation: '{{.*}}avx512f'
+// AVX10-AVX512-NOT: "avx512f"
+// AVX10-EVEX512: warning: argument unused during compilation: '{{.*}}evex512'
+// AVX10-EVEX512-NOT: "evex512"
+
 // RUN: %clang --target=i386 -musermsr %s -### -o %t.o 2>&1 | FileCheck -check-prefix=USERMSR %s
 // RUN: %clang --target=i386 -mno-usermsr %s -### -o %t.o 2>&1 | FileCheck -check-prefix=NO-USERMSR %s
 // USERMSR: "-target-feature" "+usermsr"
diff --git a/clang/test/Preprocessor/x86_target_features.c b/clang/test/Preprocessor/x86_target_features.c
index 873416d79b125..7c03ff87eefe3 100644
--- a/clang/test/Preprocessor/x86_target_features.c
+++ b/clang/test/Preprocessor/x86_target_features.c
@@ -750,6 +750,20 @@
 // AVXVNNIINT16NOAVX2-NOT: #define __AVX2__ 1
 // AVXVNNIINT16NOAVX2-NOT: #define __AVXVNNIINT16__ 1
 
+// RUN: %clang -target i686-unknown-linux-gnu -march=atom -mavx10.1 -x c -E -dM -o - %s | FileCheck  -check-prefix=AVX10_1_256 %s
+// RUN: %clang -target i686-unknown-linux-gnu -march=atom -mavx10.1-256 -x c -E -dM -o - %s | FileCheck  -check-prefix=AVX10_1_256 %s
+// RUN: %clang -target i686-unknown-linux-gnu -march=atom -mavx10.1-256 -mno-avx512f -x c -E -dM -o - %s | FileCheck  -check-prefix=AVX10_1_256 %s
+// AVX10_1_256: #define __AVX10_1__ 1
+// AVX10_1_256: #define __AVX512F__ 1
+// AVX10_1_256-NOT: __EVEX512__
+
+// RUN: %clang -target i686-unknown-linux-gnu -march=atom -mavx10.1-512 -x c -E -dM -o - %s | FileCheck  -check-prefix=AVX10_1_512 %s
+// RUN: %clang -target i686-unknown-linux-gnu -march=atom -mavx10.1-512 -mno-avx512f -x c -E -dM -o - %s | FileCheck  -check-prefix=AVX10_1_512 %s
+// RUN: %clang -target i686-unknown-linux-gnu -march=atom -mavx10.1-512 -mno-evex512 -x c -E -dM -o - %s | FileCheck  -check-prefix=AVX10_1_512 %s
+// AVX10_1_512: #define __AVX10_1__ 1
+// AVX10_1_512: #define __AVX512F__ 1
+// AVX10_1_512: #define __EVEX512__ 1
+
 // RUN: %clang -target i686-unknown-linux-gnu -march=atom -musermsr -x c -E -dM -o - %s | FileCheck  -check-prefix=USERMSR %s
 // USERMSR: #define __USERMSR__ 1
 
diff --git a/llvm/docs/ReleaseNotes.rst b/llvm/docs/ReleaseNotes.rst
index 94b43800c17bd..ade7318f2359b 100644
--- a/llvm/docs/ReleaseNotes.rst
+++ b/llvm/docs/ReleaseNotes.rst
@@ -134,6 +134,7 @@ Changes to the X86 Backend
   with C, but also fixes code generation where LLVM already assumed that the
   type matched and called into libgcc helper functions.
 * Support ISA of ``USER_MSR``.
+* Support ISA of ``AVX10.1-256`` and ``AVX10.1-512``.
 
 Changes to the OCaml bindings
 -----------------------------
diff --git a/llvm/include/llvm/TargetParser/X86TargetParser.def b/llvm/include/llvm/TargetParser/X86TargetParser.def
index 709ff8603b042..cc0f8bd31ae7d 100644
--- a/llvm/include/llvm/TargetParser/X86TargetParser.def
+++ b/llvm/include/llvm/TargetParser/X86TargetParser.def
@@ -241,6 +241,8 @@ X86_FEATURE       (SM3,             "sm3")
 X86_FEATURE       (SM4,             "sm4")
 X86_FEATURE       (AVXVNNIINT16,    "avxvnniint16")
 X86_FEATURE       (EVEX512,         "evex512")
+X86_FEATURE       (AVX10_1,         "avx10.1-256")
+X86_FEATURE       (AVX10_1_512,     "avx10.1-512")
 X86_FEATURE       (USERMSR,         "usermsr")
 // These features aren't really CPU features, but the frontend can set them.
 X86_FEATURE       (RETPOLINE_EXTERNAL_THUNK,    "retpoline-external-thunk")
diff --git a/llvm/lib/Target/X86/X86.td b/llvm/lib/Target/X86/X86.td
index f3f8d5718dfc2..556cef1f4f97e 100644
--- a/llvm/lib/Target/X86/X86.td
+++ b/llvm/lib/Target/X86/X86.td
@@ -333,6 +333,14 @@ def FeatureMOVDIRI  : SubtargetFeature<"movdiri", "HasMOVDIRI", "true",
                                        "Support movdiri instruction (direct store integer)">;
 def FeatureMOVDIR64B : SubtargetFeature<"movdir64b", "HasMOVDIR64B", "true",
                                         "Support movdir64b instruction (direct store 64 bytes)">;
+def FeatureAVX10_1 : SubtargetFeature<"avx10.1-256", "HasAVX10_1", "true",
+                                      "Support AVX10.1 up to 256-bit instruction",
+                                      [FeatureCDI, FeatureVBMI, FeatureIFMA, FeatureVNNI,
+                                       FeatureBF16, FeatureVPOPCNTDQ, FeatureVBMI2, FeatureBITALG,
+                                       FeatureVAES, FeatureVPCLMULQDQ, FeatureFP16]>;
+def FeatureAVX10_1_512 : SubtargetFeature<"avx10.1-512", "HasAVX10_1_512", "true",
+                                          "Support AVX10.1 up to 512-bit instruction",
+                                          [FeatureAVX10_1, FeatureEVEX512]>;
 
 // Ivy Bridge and newer processors have enhanced REP MOVSB and STOSB (aka
 // "string operations"). See "REP String Enhancement" in the Intel Software
diff --git a/llvm/lib/Target/X86/X86InstrInfo.td b/llvm/lib/Target/X86/X86InstrInfo.td
index cb740bc99f788..9046b6af463ac 100644
--- a/llvm/lib/Target/X86/X86InstrInfo.td
+++ b/llvm/lib/Target/X86/X86InstrInfo.td
@@ -904,6 +904,8 @@ def HasAVX       : Predicate<"Subtarget->hasAVX()">;
 def HasAVX2      : Predicate<"Subtarget->hasAVX2()">;
 def HasAVX1Only  : Predicate<"Subtarget->hasAVX() && !Subtarget->hasAVX2()">;
 def HasEVEX512   : Predicate<"Subtarget->hasEVEX512()">;
+def HasAVX10_1   : Predicate<"Subtarget->hasAVX10_1()">;
+def HasAVX10_1_512 : Predicate<"Subtarget->hasAVX10_1_512()">;
 def HasAVX512    : Predicate<"Subtarget->hasAVX512()">;
 def UseAVX       : Predicate<"Subtarget->hasAVX() && !Subtarget->hasAVX512()">;
 def UseAVX2      : Predicate<"Subtarget->hasAVX2() && !Subtarget->hasAVX512()">;
diff --git a/llvm/lib/TargetParser/Host.cpp b/llvm/lib/TargetParser/Host.cpp
index b320911d3ce27..337f918c93175 100644
--- a/llvm/lib/TargetParser/Host.cpp
+++ b/llvm/lib/TargetParser/Host.cpp
@@ -1797,6 +1797,7 @@ bool sys::getHostCPUFeatures(StringMap<bool> &Features) {
   Features["avxvnniint16"] = HasLeaf7Subleaf1 && ((EDX >> 10) & 1) && HasAVXSave;
   Features["prefetchi"]  = HasLeaf7Subleaf1 && ((EDX >> 14) & 1);
   Features["usermsr"]  = HasLeaf7Subleaf1 && ((EDX >> 15) & 1);
+  Features["avx10.1-256"] = HasLeaf7Subleaf1 && ((EDX >> 19) & 1);
 
   bool HasLeafD = MaxLevel >= 0xd &&
                   !getX86CpuIDAndInfoEx(0xd, 0x1, &EAX, &EBX, &ECX, &EDX);
@@ -1815,6 +1816,11 @@ bool sys::getHostCPUFeatures(StringMap<bool> &Features) {
       MaxLevel >= 0x19 && !getX86CpuIDAndInfo(0x19, &EAX, &EBX, &ECX, &EDX);
   Features["widekl"] = HasLeaf7 && HasLeaf19 && ((EBX >> 2) & 1);
 
+  bool HasLeaf24 =
+      MaxLevel >= 0x24 && !getX86CpuIDAndInfo(0x24, &EAX, &EBX, &ECX, &EDX);
+  Features["avx10.1-512"] =
+      Features["avx10.1-256"] && HasLeaf24 && ((EBX >> 18) & 1);
+
   return true;
 }
 #elif defined(__linux__) && (defined(__arm__) || defined(__aarch64__))
diff --git a/llvm/lib/TargetParser/X86TargetParser.cpp b/llvm/lib/TargetParser/X86TargetParser.cpp
index 94849f915daa1..f9aece5aaa24e 100644
--- a/llvm/lib/TargetParser/X86TargetParser.cpp
+++ b/llvm/lib/TargetParser/X86TargetParser.cpp
@@ -611,6 +611,15 @@ constexpr FeatureBitset ImpliedFeaturesWIDEKL = FeatureKL;
 // AVXVNNI Features
 constexpr FeatureBitset ImpliedFeaturesAVXVNNI = FeatureAVX2;
 
+// AVX10 Features
+constexpr FeatureBitset ImpliedFeaturesAVX10_1 =
+    FeatureAVX512CD | FeatureAVX512VBMI | FeatureAVX512IFMA |
+    FeatureAVX512VNNI | FeatureAVX512BF16 | FeatureAVX512VPOPCNTDQ |
+    FeatureAVX512VBMI2 | FeatureAVX512BITALG | FeatureVAES | FeatureVPCLMULQDQ |
+    FeatureAVX512FP16;
+constexpr FeatureBitset ImpliedFeaturesAVX10_1_512 =
+    FeatureAVX10_1 | FeatureEVEX512;
+
 constexpr FeatureInfo FeatureInfos[X86::CPU_FEATURE_MAX] = {
 #define X86_FEATURE(ENUM, STR) {{"+" STR}, ImpliedFeatures##ENUM},
 #include "llvm/TargetParser/X86TargetParser.def"