diff --git a/llvm/utils/gn/build/BUILD.gn b/llvm/utils/gn/build/BUILD.gn
index ee8a83c946a3e8..522f54f734da54 100644
--- a/llvm/utils/gn/build/BUILD.gn
+++ b/llvm/utils/gn/build/BUILD.gn
@@ -5,7 +5,7 @@ import("//llvm/utils/gn/build/toolchain/compiler.gni")
 import("//llvm/utils/gn/build/toolchain/target_flags.gni")
 
 declare_args() {
-  # Whether to build everything with coverage information.
+  # Whether to build everything with test coverage information.
   # After building with this, run tests and then run
   #    llvm/utils/prepare-code-coverage-artifact.py \
   #        --compilation-dir=out/gn \
@@ -14,6 +14,20 @@ declare_args() {
   # to generate a HTML report for the binaries passed in the last line.
   llvm_build_instrumented_coverage = false
 
+  # Whether to build everything with instrumentation for PGO
+  # After building with this:
+  # 1. Remove old profile data with `rm *.profraw`
+  # 2. Run the built instrumented binaries.
+  #    This will produce *.profraw files in the current working directory.
+  # 3. Run `llvm-profdata merge *.profraw -o llvm.profdata` to merge them.
+  # 4. Then build again, with this set to false, and with
+  #    `llvm_pgo_use = "//llvm.profdata"` set to use the created profile.
+  llvm_pgo_instrument = false
+
+  # If non-empty, path to merged profiling data used for optimization
+  # See documentation for llvm_pgo_instrument for how to create profile data.
+  llvm_pgo_use = ""
+
   # If set, puts relative paths in debug info.
   # Makes the build output independent of the build directory, but makes
   # most debuggers harder to use. See "Getting to local determinism" and
@@ -28,6 +42,12 @@ declare_args() {
 
 assert(!llvm_build_instrumented_coverage || is_clang,
        "llvm_build_instrumented_coverage requires clang as host compiler")
+assert(!llvm_pgo_instrument || is_clang,
+       "llvm_pgo_instrument requires clang as host compiler")
+assert(llvm_pgo_use == "" || is_clang,
+       "llvm_pgo_use requires clang as host compiler")
+assert(!llvm_pgo_instrument || llvm_pgo_use == "",
+       "set at most one of llvm_pgo_instrument and llvm_pgo_use")
 
 config("compiler_defaults") {
   defines = []
@@ -272,6 +292,23 @@ config("compiler_defaults") {
       ldflags += [ "-fprofile-instr-generate" ]
     }
   }
+  if (llvm_pgo_instrument) {
+    cflags += [ "-fprofile-generate" ]
+    if (current_os != "win") {
+      ldflags += [ "-fprofile-generate" ]
+    }
+  }
+  if (llvm_pgo_use != "") {
+    cflags += [
+      "-fprofile-use=" + rebase_path(llvm_pgo_use, root_build_dir),
+
+      # There are always quite a few diags like
+      #     warning: foo.cpp: Function control flow change detected
+      #              (hash mismatch) [-Wbackend-plugin]
+      # in a PGO build. Since they're not unexpected, silence them.
+      "-Wno-backend-plugin",
+    ]
+  }
 
   # Deterministic build setup, see
   # http://blog.llvm.org/2019/11/deterministic-builds-with-clang-and-lld.html