diff --git a/clang/lib/Driver/ToolChains/Clang.cpp b/clang/lib/Driver/ToolChains/Clang.cpp
index 3aff071d753943..58d6215670ad6d 100644
--- a/clang/lib/Driver/ToolChains/Clang.cpp
+++ b/clang/lib/Driver/ToolChains/Clang.cpp
@@ -6338,6 +6338,12 @@ void Clang::ConstructJob(Compilation &C, const JobAction &JA,
           << A->getAsString(Args) << TripleStr;
     }
   }
+  if (Arg *A = Args.getLastArgNoClaim(options::OPT_pg)) {
+    if (TC.getTriple().isOSzOS()) {
+      D.Diag(diag::err_drv_unsupported_opt_for_target)
+          << A->getAsString(Args) << TripleStr;
+    }
+  }
 
   if (Args.getLastArg(options::OPT_fapple_kext) ||
       (Args.hasArg(options::OPT_mkernel) && types::isCXX(InputType)))
diff --git a/clang/test/Driver/zos-profiling-error.c b/clang/test/Driver/zos-profiling-error.c
new file mode 100644
index 00000000000000..e969dc31a245a5
--- /dev/null
+++ b/clang/test/Driver/zos-profiling-error.c
@@ -0,0 +1,2 @@
+// RUN: %clang 2>&1 -### --target=s390x-none-zos -pg -S %s | FileCheck -check-prefix=FAIL-PG-NAME %s
+// FAIL-PG-NAME: error: unsupported option '-pg' for target 's390x-none-zos'