diff --git a/llvm/lib/Target/X86/X86TargetTransformInfo.cpp b/llvm/lib/Target/X86/X86TargetTransformInfo.cpp
index 513753032b1a2..fa8e979a1ac48 100644
--- a/llvm/lib/Target/X86/X86TargetTransformInfo.cpp
+++ b/llvm/lib/Target/X86/X86TargetTransformInfo.cpp
@@ -5088,6 +5088,7 @@ InstructionCost X86TTIImpl::getInterleavedMemoryOpCostAVX2(
       {4, MVT::v2i16, 6}, // (load 8i16 and) deinterleave into 4 x 2i16
       {4, MVT::v4i16, 17}, // (load 16i16 and) deinterleave into 4 x 4i16
       {4, MVT::v8i16, 33}, // (load 32i16 and) deinterleave into 4 x 8i16
+      {4, MVT::v16i16, 75}, // (load 64i16 and) deinterleave into 4 x 16i16
 
       {8, MVT::v8i32, 40} // (load 64i32 and) deinterleave into 8 x 8i32
   };
@@ -5116,6 +5117,7 @@ InstructionCost X86TTIImpl::getInterleavedMemoryOpCostAVX2(
       {4, MVT::v2i16, 2},  // interleave 4 x 2i16 into 8i16 (and store)
       {4, MVT::v4i16, 6},  // interleave 4 x 4i16 into 16i16 (and store)
       {4, MVT::v8i16, 10},  // interleave 4 x 8i16 into 32i16 (and store)
+      {4, MVT::v16i16, 32},  // interleave 4 x 16i16 into 64i16 (and store)
   };
 
   if (Opcode == Instruction::Load) {
diff --git a/llvm/test/Analysis/CostModel/X86/interleaved-load-i16-stride-4.ll b/llvm/test/Analysis/CostModel/X86/interleaved-load-i16-stride-4.ll
index cbb5445df7841..d2870ce922146 100644
--- a/llvm/test/Analysis/CostModel/X86/interleaved-load-i16-stride-4.ll
+++ b/llvm/test/Analysis/CostModel/X86/interleaved-load-i16-stride-4.ll
@@ -12,7 +12,7 @@ target triple = "x86_64-unknown-linux-gnu"
 ; CHECK: LV: Found an estimated cost of 7 for VF 2 For instruction:   %v0 = load i16, i16* %in0, align 2
 ; CHECK: LV: Found an estimated cost of 18 for VF 4 For instruction:   %v0 = load i16, i16* %in0, align 2
 ; CHECK: LV: Found an estimated cost of 35 for VF 8 For instruction:   %v0 = load i16, i16* %in0, align 2
-; CHECK: LV: Found an estimated cost of 228 for VF 16 For instruction:   %v0 = load i16, i16* %in0, align 2
+; CHECK: LV: Found an estimated cost of 79 for VF 16 For instruction:   %v0 = load i16, i16* %in0, align 2
 ; CHECK: LV: Found an estimated cost of 456 for VF 32 For instruction:   %v0 = load i16, i16* %in0, align 2
 ; CHECK-NOT: LV: Found an estimated cost of {{[0-9]+}} for VF {{[0-9]+}} For instruction:   %v0 = load i16, i16* %in0, align 2
 
diff --git a/llvm/test/Analysis/CostModel/X86/interleaved-store-i16-stride-4.ll b/llvm/test/Analysis/CostModel/X86/interleaved-store-i16-stride-4.ll
index c9a13111bb441..c614be256d066 100644
--- a/llvm/test/Analysis/CostModel/X86/interleaved-store-i16-stride-4.ll
+++ b/llvm/test/Analysis/CostModel/X86/interleaved-store-i16-stride-4.ll
@@ -12,7 +12,7 @@ target triple = "x86_64-unknown-linux-gnu"
 ; CHECK: LV: Found an estimated cost of 3 for VF 2 For instruction:   store i16 %v3, i16* %out3, align 2
 ; CHECK: LV: Found an estimated cost of 7 for VF 4 For instruction:   store i16 %v3, i16* %out3, align 2
 ; CHECK: LV: Found an estimated cost of 12 for VF 8 For instruction:   store i16 %v3, i16* %out3, align 2
-; CHECK: LV: Found an estimated cost of 228 for VF 16 For instruction:   store i16 %v3, i16* %out3, align 2
+; CHECK: LV: Found an estimated cost of 36 for VF 16 For instruction:   store i16 %v3, i16* %out3, align 2
 ; CHECK: LV: Found an estimated cost of 456 for VF 32 For instruction:   store i16 %v3, i16* %out3, align 2
 ; CHECK-NOT: LV: Found an estimated cost of {{[0-9]+}} for VF {{[0-9]+}} For instruction:   store i16 %v3, i16* %out3, align 2