diff --git a/llvm/lib/Transforms/IPO/GlobalOpt.cpp b/llvm/lib/Transforms/IPO/GlobalOpt.cpp
index d7edd1288309b..f88d51f443bcf 100644
--- a/llvm/lib/Transforms/IPO/GlobalOpt.cpp
+++ b/llvm/lib/Transforms/IPO/GlobalOpt.cpp
@@ -2551,7 +2551,8 @@ static bool OptimizeNonTrivialIFuncs(
         }))
       continue;
 
-    assert(!Callees.empty() && "Expecting successful collection of versions");
+    if (Callees.empty())
+      continue;
 
     LLVM_DEBUG(dbgs() << "Statically resolving calls to function "
                       << Resolver->getName() << "\n");
diff --git a/llvm/test/Transforms/GlobalOpt/resolve-indirect-ifunc.ll b/llvm/test/Transforms/GlobalOpt/resolve-indirect-ifunc.ll
new file mode 100644
index 0000000000000..16c529b42a82f
--- /dev/null
+++ b/llvm/test/Transforms/GlobalOpt/resolve-indirect-ifunc.ll
@@ -0,0 +1,11 @@
+; NOTE: Assertions have been autogenerated by utils/update_test_checks.py UTC_ARGS: --version 5
+; RUN: opt --passes=globalopt -o - -S < %s | FileCheck %s
+
+define ptr @f1() {
+; CHECK-LABEL: define ptr @f1() {
+; CHECK-NEXT:    unreachable
+;
+  unreachable
+}
+
+@i1 = ifunc void(), ptr @f1