diff --git a/mlir/include/mlir-c/IR.h b/mlir/include/mlir-c/IR.h
index 061d7620ba077..c464e4da66f17 100644
--- a/mlir/include/mlir-c/IR.h
+++ b/mlir/include/mlir-c/IR.h
@@ -634,6 +634,10 @@ MLIR_CAPI_EXPORTED MlirContext mlirOperationGetContext(MlirOperation op);
 /// Gets the location of the operation.
 MLIR_CAPI_EXPORTED MlirLocation mlirOperationGetLocation(MlirOperation op);
 
+/// Sets the location of the operation.
+MLIR_CAPI_EXPORTED void mlirOperationSetLocation(MlirOperation op,
+                                                 MlirLocation loc);
+
 /// Gets the type id of the operation.
 /// Returns null if the operation does not have a registered operation
 /// description.
diff --git a/mlir/lib/Bindings/Python/IRCore.cpp b/mlir/lib/Bindings/Python/IRCore.cpp
index 83a8757bb72c7..c20b2111c071e 100644
--- a/mlir/lib/Bindings/Python/IRCore.cpp
+++ b/mlir/lib/Bindings/Python/IRCore.cpp
@@ -3485,15 +3485,21 @@ void mlir::python::populateIRCore(nb::module_ &m) {
           },
           "Shortcut to get an op result if it has only one (throws an error "
           "otherwise).")
-      .def_prop_ro(
+      .def_prop_rw(
           "location",
           [](PyOperationBase &self) {
             PyOperation &operation = self.getOperation();
             return PyLocation(operation.getContext(),
                               mlirOperationGetLocation(operation.get()));
           },
-          "Returns the source location the operation was defined or derived "
-          "from.")
+          [](PyOperationBase &self, const PyLocation &location) {
+            PyOperation &operation = self.getOperation();
+            mlirOperationSetLocation(operation.get(), location.get());
+          },
+          nb::for_getter("Returns the source location the operation was "
+                         "defined or derived from."),
+          nb::for_setter("Sets the source location the operation was defined "
+                         "or derived from."))
       .def_prop_ro("parent",
                    [](PyOperationBase &self)
                        -> std::optional<nb::typed<nb::object, PyOperation>> {
diff --git a/mlir/lib/CAPI/IR/IR.cpp b/mlir/lib/CAPI/IR/IR.cpp
index e9844a7cc1909..188186598c5c5 100644
--- a/mlir/lib/CAPI/IR/IR.cpp
+++ b/mlir/lib/CAPI/IR/IR.cpp
@@ -656,6 +656,10 @@ MlirLocation mlirOperationGetLocation(MlirOperation op) {
   return wrap(unwrap(op)->getLoc());
 }
 
+void mlirOperationSetLocation(MlirOperation op, MlirLocation loc) {
+  unwrap(op)->setLoc(unwrap(loc));
+}
+
 MlirTypeID mlirOperationGetTypeID(MlirOperation op) {
   if (auto info = unwrap(op)->getRegisteredInfo())
     return wrap(info->getTypeID());
diff --git a/mlir/test/python/ir/operation.py b/mlir/test/python/ir/operation.py
index 4a3625c953d52..cb4cfc8c8a6ec 100644
--- a/mlir/test/python/ir/operation.py
+++ b/mlir/test/python/ir/operation.py
@@ -696,6 +696,7 @@ def testOperationPrint():
     # CHECK: resource1: "0x08
     module.operation.print(large_elements_limit=2)
 
+
 # CHECK-LABEL: TEST: testKnownOpView
 @run
 def testKnownOpView():
@@ -969,6 +970,13 @@ def testOperationLoc():
         assert op.location == loc
         assert op.operation.location == loc
 
+        another_loc = Location.name("another_loc")
+        op.location = another_loc
+        assert op.location == another_loc
+        assert op.operation.location == another_loc
+        # CHECK: loc("another_loc")
+        print(op.location)
+
 
 # CHECK-LABEL: TEST: testModuleMerge
 @run