diff --git a/clang/docs/ReleaseNotes.rst b/clang/docs/ReleaseNotes.rst
index d2e5bd284d350..7d07c3d9a0be7 100644
--- a/clang/docs/ReleaseNotes.rst
+++ b/clang/docs/ReleaseNotes.rst
@@ -250,6 +250,8 @@ Non-comprehensive list of changes in this release
 
 - ``__builtin_assume_dereferenceable`` now accepts non-constant size operands.
 
+- Fixed a crash when the second argument to ``__builtin_assume_aligned`` was not constant (#GH161314)
+
 New Compiler Flags
 ------------------
 - New option ``-fno-sanitize-debug-trap-reasons`` added to disable emitting trap reasons into the debug info when compiling with trapping UBSan (e.g. ``-fsanitize-trap=undefined``).
diff --git a/clang/lib/CodeGen/CGExprScalar.cpp b/clang/lib/CodeGen/CGExprScalar.cpp
index f319b176513f8..c961222766475 100644
--- a/clang/lib/CodeGen/CGExprScalar.cpp
+++ b/clang/lib/CodeGen/CGExprScalar.cpp
@@ -465,11 +465,16 @@ class ScalarExprEmitter
       return nullptr;
 
     if (Value *Result = ConstantEmitter(CGF).tryEmitConstantExpr(E)) {
-      if (E->isGLValue())
+      if (E->isGLValue()) {
+        // This was already converted to an rvalue when it was constant
+        // evaluated.
+        if (E->hasAPValueResult() && !E->getAPValueResult().isLValue())
+          return Result;
         return CGF.EmitLoadOfScalar(
             Address(Result, CGF.convertTypeForLoadStore(E->getType()),
                     CGF.getContext().getTypeAlignInChars(E->getType())),
             /*Volatile*/ false, E->getType(), E->getExprLoc());
+      }
       return Result;
     }
     return Visit(E->getSubExpr());
diff --git a/clang/lib/Sema/SemaChecking.cpp b/clang/lib/Sema/SemaChecking.cpp
index 7ce3513fe0969..3cc61b167ba98 100644
--- a/clang/lib/Sema/SemaChecking.cpp
+++ b/clang/lib/Sema/SemaChecking.cpp
@@ -5954,6 +5954,9 @@ bool Sema::BuiltinAssumeAligned(CallExpr *TheCall) {
     if (Result > Sema::MaximumAlignment)
       Diag(TheCall->getBeginLoc(), diag::warn_assume_aligned_too_great)
           << SecondArg->getSourceRange() << Sema::MaximumAlignment;
+
+    TheCall->setArg(1,
+                    ConstantExpr::Create(Context, SecondArg, APValue(Result)));
   }
 
   if (NumArgs > 2) {
diff --git a/clang/test/SemaCXX/builtin-assume-aligned.cpp b/clang/test/SemaCXX/builtin-assume-aligned.cpp
index 48bd8414fc50a..30296c72c6be8 100644
--- a/clang/test/SemaCXX/builtin-assume-aligned.cpp
+++ b/clang/test/SemaCXX/builtin-assume-aligned.cpp
@@ -47,3 +47,16 @@ constexpr void *s1 = __builtin_assume_aligned(x, 32);
 constexpr void *s2 = __builtin_assume_aligned(x, 32, 5);
 constexpr void *s3 = __builtin_assume_aligned(x, 32, -1);
 
+
+constexpr int add(int a, int b) {
+  return a+b;
+}
+constexpr void *c1 = __builtin_assume_aligned(p, add(1,1));
+constexpr void *c2 = __builtin_assume_aligned(p, add(2,1)); // expected-error {{not a power of 2}}
+
+constexpr long kAlignment = 128;
+long AllocateAlignedBytes_payload;
+void AllocateAlignedBytes() {
+  void *m = __builtin_assume_aligned(
+      reinterpret_cast<void *>(AllocateAlignedBytes_payload), kAlignment);
+}