diff --git a/.gitattributes b/.gitattributes
index 6b281f33f737d..142d6689f1088 100644
--- a/.gitattributes
+++ b/.gitattributes
@@ -1,3 +1,5 @@
+clang/bindings/python/.git_archival.txt  export-subst
+
 libcxx/src/**/*.cpp     merge=libcxx-reformat
 libcxx/include/**/*.h   merge=libcxx-reformat
 
diff --git a/.github/workflows/release-clang-pypi.yml b/.github/workflows/release-clang-pypi.yml
new file mode 100644
index 0000000000000..8c0b00a574cf5
--- /dev/null
+++ b/.github/workflows/release-clang-pypi.yml
@@ -0,0 +1,111 @@
+name: Release Clang Python Bindings
+
+permissions:
+  contents: read
+
+on:
+  push:
+    branches:
+      - main
+      - release/*
+    paths:
+      - .github/workflows/release-clang-pypi.yml
+      - 'clang/bindings/python/**'
+
+  pull_request:
+    paths:
+      - .github/workflows/release-clang-pypi.yml
+      - 'clang/bindings/python/**'
+
+  workflow_dispatch:
+    inputs:
+      release-version:
+        description: 'Release Version'
+        required: false
+        type: string
+
+  workflow_call:
+    inputs:
+      release-version:
+        description: 'Release Version'
+        required: true
+        type: string
+    secrets:
+      RELEASE_TASKS_USER_TOKEN:
+        description: "Secret used to check user permissions."
+        required: false
+
+jobs:
+  build-release:
+    if: github.repository_owner == 'llvm' || github.event_name == 'workflow_dispatch'
+    runs-on: ubuntu-24.04
+    steps:
+      - name: Checkout LLVM (tagged release)
+        if: inputs.release-version != ''
+        uses: actions/checkout@08c6903cd8c0fde910a37f88322edcfb5dd907a8 # v5.0.0
+        with:
+          ref: "llvmorg-${{ inputs.release-version }}"
+          fetch-depth: 0
+          sparse-checkout: clang/bindings/python/
+
+      - name: Checkout LLVM (latest commit)
+        if: inputs.release-version == ''
+        uses: actions/checkout@08c6903cd8c0fde910a37f88322edcfb5dd907a8 # v5.0.0
+        with:
+          fetch-depth: 0
+          sparse-checkout: clang/bindings/python/
+
+      - uses: actions/setup-python@e797f83bcb11b83ae66e0230d6156d7c80228e7c # v6.0.0
+        with:
+          python-version: '3.13'
+
+      - name: Package Clang Python Bindings
+        working-directory: clang/bindings/python
+        run: |
+          pip install build twine
+          python -m build
+          python -m twine check dist/*
+          
+      - name: Upload Clang Python Bindings package dist artifacts
+        uses: actions/upload-artifact@330a01c490aca151604b8cf639adc76d48f6c5d4 # v5.0.0
+        with:
+          name: python-package-dist
+          path: clang/bindings/python/dist
+
+  pypi-publish:
+    name: Upload release to PyPI
+    runs-on: ubuntu-24.04
+    needs: build-release
+    # Only run this job in the main llvm repository when a release version is provided.
+    if: github.repository_owner == 'llvm' && inputs.release-version != ''
+    environment:
+      name: pypi
+      url: https://pypi.org/p/clang
+    permissions:
+      id-token: write  # IMPORTANT: this permission is mandatory for trusted publishing
+    steps:
+      - name: Checkout github-upload-release.py for permissions check
+        uses: actions/checkout@08c6903cd8c0fde910a37f88322edcfb5dd907a8 # v5.0.0
+        with:
+          sparse-checkout: llvm/utils/release/github-upload-release.py
+
+      - name: Install dependencies for github-upload-release.py
+        run: |
+          sudo apt-get update
+          sudo apt-get install -y python3-github
+
+      - name: Check Permissions
+        env:
+          GITHUB_TOKEN: ${{ github.token }}
+          USER_TOKEN: ${{ secrets.RELEASE_TASKS_USER_TOKEN }}
+        run: |
+          ./llvm/utils/release/github-upload-release.py --token "$GITHUB_TOKEN" --user ${{ github.actor }} --user-token "$USER_TOKEN" check-permissions
+
+      - name: Download Python package dist artifacts
+        uses: actions/download-artifact@018cc2cf5baa6db3ef3c5f8a56943fffe632ef53 # v6.0.0
+        with:
+            name: python-package-dist
+            path: dist
+
+      - name: Publish package distributions to PyPI
+        uses: pypa/gh-action-pypi-publish@ed0c53931b1dc9bd32cbe73a98c7f6766f8a527e # v1.13.0
\ No newline at end of file
diff --git a/clang/bindings/python/.git_archival.txt b/clang/bindings/python/.git_archival.txt
new file mode 100644
index 0000000000000..7876d4af4c620
--- /dev/null
+++ b/clang/bindings/python/.git_archival.txt
@@ -0,0 +1,3 @@
+node: $Format:%H$
+node-date: $Format:%cI$
+describe-name: $Format:%(describe:tags=true,match=llvmorg-*[0-9]*)$
diff --git a/clang/bindings/python/.gitignore b/clang/bindings/python/.gitignore
new file mode 100644
index 0000000000000..1641a745fb682
--- /dev/null
+++ b/clang/bindings/python/.gitignore
@@ -0,0 +1,21 @@
+# setuptools_scm auto-generated version file
+_version.py
+
+# Byte-compiled / optimized / DLL files
+__pycache__/
+*.py[cod]
+*$py.class
+
+# Distribution / packaging
+build/
+dist/
+*.egg-info/
+
+# Environments
+.env
+.venv
+env/
+venv/
+ENV/
+env.bak/
+venv.bak/
diff --git a/clang/bindings/python/pyproject.toml b/clang/bindings/python/pyproject.toml
new file mode 100644
index 0000000000000..69fd628e8222a
--- /dev/null
+++ b/clang/bindings/python/pyproject.toml
@@ -0,0 +1,43 @@
+[build-system]
+requires = ["hatchling>=1.27", "hatch-vcs>=0.4"]
+build-backend = "hatchling.build"
+
+[project]
+name = "clang"
+description = "clang python bindings"
+readme = {file = "README.txt", content-type = "text/plain"}
+
+license = "Apache-2.0 WITH LLVM-exception"
+authors = [
+    { name = "LLVM" }
+]
+keywords = ["llvm", "clang", "libclang"]
+classifiers = [
+    "Intended Audience :: Developers",
+    "Development Status :: 5 - Production/Stable",
+    "Topic :: Software Development :: Compilers",
+    "Operating System :: OS Independent",
+    "Programming Language :: Python :: 3",
+]
+requires-python = ">=3.10"
+dynamic = ["version"]
+
+[project.urls]
+Homepage = "https://clang.llvm.org/"
+Download = "https://llvm.org/releases/download.html"
+Discussions = "https://discourse.llvm.org/"
+"Issue Tracker" = "https://github.com/llvm/llvm-project/issues"
+"Source Code" = "https://github.com/llvm/llvm-project/tree/main/clang/bindings/python"
+
+[tool.hatch.version]
+source = "vcs"
+version-scheme = "no-guess-dev"
+# regex version capture group gets x.y.z with optional -rcN, -aN, -bN suffixes; -init is just consumed
+tag-pattern = "^llvmorg-(?P<version>\\d+(?:\\.\\d+)*(?:-rc\\d+)?)"
+
+[tool.hatch.build.hooks.vcs]
+version-file = "clang/_version.py"
+
+[tool.hatch.version.raw-options]
+search_parent_directories = true
+version_scheme = "no-guess-dev"