Microsoft eXtended Flow Guard (XFG) is a control-flow integrity (CFI) technique that extends CFG with function call signatures. Each signature is 8 bytes long, and is located right before the target function. Since the signature is located in the code section, x64dbg gets confused and shows it as random instructions. This also often makes x64dbg unable to correctly disassemble the beginning of the function.
The plugin goes over all XFG function call signatures and marks them as 8-byte integers, creating a clear separation between the signature and the function.
The plugin also has the options to add comments with the possible indirect call target functions, and to add xrefs between the indirect call and each target function for easy navigation.
For more details, refer to the relevant blog post.